Bariatric surgery in adolescents with severe obesity: Review and state of the art in France.

Severe obesity (body mass index>120% of BMI IOTF-30 cut off) and morbid obesity (BMI>140% of BMI IOTF-30 cut off) affect 5 to 10% of obese adolescents in France. Organic complications can be found in about 50% of these patients, and depressive symptoms in one-third of them. Finally, over 70% will suffer from adult morbid obesity associated with a marked increase in morbidity and mortality.

In Vitro Effects of the Endocrine Disruptor p,p'-DDT on Human Follitropin Receptor.

Background: 1-chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene (p,p'-DDT) is a persistent environmental endocrine disruptor (ED). Several studies have shown an association between p,p'-DDT exposure and reproductive abnormalities.

Objectives: To investigate the putative effects of p,p'-DDT on the human follitropin receptor (FSHR) function.

Birth Weight Is Associated With the IGF-1 Response to GH in Children: Programming of the Anabolic Action of GH?

Context: Intrauterine programming of the somatotropic axis has been hypothesized in cases of intrauterine growth retardation.

Objective: The objective of the study was to study the effects of birth weight and body composition on GH sensitivity.

Design: This was a cross-sectional study with a single GH administration to assess GH sensitivity.