Publications by authors named "Mathilde Farizon"

Healthcare-associated bacteremia is associated with increased morbidity and mortality. In nursing homes, these infections remain under-documented. We investigated invasive device-associated bacteremia in residents.

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Introduction: Central venous catheters are critical in preterm neonatal care but increase the risk of central line-associated bloodstream infections (CLABSIs). The incidence of -associated CLABSIs in French neonates is increasing, but the mechanisms underlying this trend remain unclear.

Methods: We examined microorganisms in 108 central line infusion sets used in preterm infants across 12 neonatal intensive care units, and collected at the time of removal.

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Hematology patients require central venous catheters for cancer treatment and nutrition, which increases their risk of intravascular device-associated bacteremia. In the absence of recent data, we investigated intravascular device-associated bacteremia in this specific context. A three-month surveillance was conducted annually in 27 hematology wards, using a protocol derived from the HAI-Net ICU ECDC protocol (2020-2024).

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Article Synopsis
  • - The study aimed to examine the use of sterile gloves by healthcare workers (HCWs) during manipulations of central line catheters, which can carry a risk of infections like bacteremia.
  • - Observations revealed that 72% of HCWs used sterile gloves, while 19% did not wear any gloves at all, with microbial contamination found on the fingertips of 28% of those tested.
  • - The findings indicated that fingertip contamination was lower among HCWs who wore sterile gloves, highlighting the importance of glove use in preventing infections during central line handling.
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Background: Central catheters expose ICU patients at risk of catheter-related bloodstream infections. A mechanism by which these infections occur is the contamination of the catheter during its insertion if aseptic techniques are not strictly applied. Recent studies suggest that the use of ultrasound guidance (USG) may increase the risk of catheter contamination during insertion.

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Background: Patients who have short peripheral venous catheters (PVC) face an elevated risk of developing bloodstream infections. Preventing catheter-related infections relies on implementing multiple measures, including practicing proper hand hygiene (HH) during catheter placement.

Methods: We conducted a four-part study: (1) an evaluation of HH practices through direct observation of PVC placements, coupled with the study of the microbial flora of the HCWs fingers just before the placement; (2) the development of an educational tool based on the collected observational and microbiological data; (3) the training to the HCWs observed during the first part, using this tool; and (4) the subsequent observation of the trained HCWs to measure the impact of the training on practice improvement.

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