Publications by authors named "Mathieu Rousseau-Gagnon"

Article Synopsis
  • Alport syndrome is linked to three genes (COL4A3, COL4A4, COL4A5) and is marked by kidney issues like glomerulosclerosis and changes in the glomerular basement membrane.
  • A study reported a mother and son with COL4A5-related Alport syndrome, sharing unusual kidney biopsy results and a specific genetic variant (p.Gly1170Ser).
  • Findings indicate that changes in collagen expression in Bowman's capsule might be more affected by mutations in COL4A5, suggesting that certain genetic variants can play a significant role in how the disease presents.
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Rationale: Synthetic adrenocorticotropic hormone (Tetracosactide) has been used in the treatment of refractory glomerular diseases. Literature surrounding the use of this medication is limited to small case series and there is conflicting data on the rate of adverse events associated with this medication.

Presenting Concerns Of The Patient: Glomerulonephritis not in remission after at least 6 months of treatment with conservative care.

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Context: Team-based learning (TBL) is a flipped-classroom approach requiring students to study before class. Fully flipped curricula usually have fewer in-class hours. However, for practical reasons, several programs implement a few weeks of TBL without adjusting the semester timetable.

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Background: Health literacy refers to the ability of individuals to gain access to, use, and understand health information and services in order to maintain a good health. It is especially important in nephrology due to the complexity of chronic kidney disease (CKD). The present study sought to define health literacy levels in patients followed in predialysis clinic, in-center dialysis (ICHD), peritoneal dialysis (PD) and home hemodialysis (HHD).

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Article Synopsis
  • * A retrospective study reviewed data from HHD patients to track infections and assess self-cannulation errors using a nurse-administered checklist; findings revealed that while overall infection rates were similar among patients, those with five or more errors had a significantly higher infection rate.
  • * The results suggest that longer HHD experience may correlate with poorer vascular access techniques, highlighting the need for regular audits to identify and reduce errors, and indicating that further research on this topic is necessary.
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Introduction: In cases of myeloma cast nephropathy in need of haemodialysis (HD), reduction of free light chains using HD with High-Cut-Off filters (HCO-HD), in combination with chemotherapy, may be associated with better renal recovery. The aim of the present study is to evaluate the effectiveness of haemodiafiltration (HDF) in reducing free light chain levels using a less expensive heat sterilized high-flux polyphenylene HF dialyzer (HF-HDF).

Methods: In a single-centre prospective cohort study, 327 dialysis sessions were performed using a 2.

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A 67-year-old man was evaluated for haematuria, with a rising creatinine level from 88 to 906 µmol/L and positive c-anti-neutrophil cytoplasm antibody (ANCA)/anti-proteinase 3 (anti-PR3). A kidney biopsy revealed necrotizing glomerulonephritis with a 'full-house' pattern on immunofluorescence microscopy. Echocardiography and blood cultures growing Gemella sanguinis diagnosed endocarditis.

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Quadriceps muscle weakness and increased fatigability are well described in patients with chronic obstructive pulmonary disease (COPD). Whether these functional alterations also exist in distal leg muscles in patients with COPD is uncertain. Fifteen patients with COPD and 15 aged-matched healthy controls performed a 12-minute standardized treadmill exercise during which a fixed total expense of 40 Kcal was reached.

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Delayed graft function (DGF) has a negative impact on graft survival in donation after brain death (DBD) but not for donation after cardiac death (DCD) kidneys. However, older donor age is associated with graft loss in DCD transplants. We sought to examine the interaction between donor age and DGF in DBD kidneys.

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