Publications by authors named "Mathias Velarde"
Introduction: Gait recovery remains one of the most determining factors in social participation for poststroke individuals, in whom ankle dorsiflexor function is closely related to gait speed. Focal muscle vibration has shown promising neurophysiological and clinical effects in neuromotor recovery. However, it remains to be determined whether tibialis anterior focal muscle vibration applied to the paretic limb could improve walking speed when implemented in early rehabilitation after stroke occurrence.
View Article and Find Full Text PDFMolecular determinants of skeletal muscle force loss in response to 5 days of dry immersion in human.
J Cachexia Sarcopenia Muscle
December 2024
Background: Astronauts in Earth's orbit experience microgravity, resulting in a decline of skeletal muscle mass and function. On Earth, models simulating microgravity have shown that the extent of the loss in muscle force is greater than the loss in muscle mass. The reasons behind this disproportionate loss of muscle force are still poorly understood.
View Article and Find Full Text PDFArticle Synopsis
- Sepsis in ICU patients leads to muscle mass loss and decreased function, contributing to long-term disability.
- A study tested whether disabling the myostatin gene, which normally inhibits muscle growth, could help prevent muscle wasting in septic mice, but results showed no benefits.
- Both wild-type and myostatin knock-out mice experienced similar muscle mass and strength loss after sepsis, suggesting that targeting myostatin may not effectively improve outcomes in muscle wasting related to sepsis.