Clinics (Sao Paulo)
June 2025
Neurosurg Rev
June 2025
Background And Objectives: The reverse Trendelenburg position (rTP) tends to reduce jugular bulb pressure (JBP) and intracranial pressure (ICP), and thus improves the operative conditions by increasing brain relaxation. However, through simultaneous decreases in MAP, the cerebral perfusion pressure (CPP) can theoretically decrease, remain unchanged, or increase. We aim to evaluate the effects of rTP on ICP, MAP, JBP, and CPP in intracranial neurosurgery in order to determine the optimal degree of rTP to provide best operating conditions.
View Article and Find Full Text PDFExternal ventricular drainage (EVD) is a mainstay for intraventricular hemorrhage (IVH) treatment, improving ventricular clearance and reducing mortality but with suboptimal complications and morbidity. Meanwhile, several studies have shown that neuroendoscopic drainage (NED) provides superior results and is a promising therapy. Thus, we aimed to compare NED and EVD in patients with IVH.
View Article and Find Full Text PDFObjective: To assess the performance of pembrolizumab for the treatment of Gestational Trophoblastic Neoplasia (GTN).
Methods: The Medical Subject Headings related to immunotherapy/pembrolizumab and GTN were used alone or in combination to retrieve relevant articles. The authors searched in EMBASE, MEDLINE/PubMed, Elsevier's Scopus, and Web of Science until November/2024.
Background: Liver transplant (LT) patients have become older and sicker. The rate of post-LT major adverse cardiovascular events (MACE) has increased, and this in turn raises 30-d post-LT mortality. Noninvasive cardiac stress testing loses accuracy when applied to pre-LT cirrhotic patients.
View Article and Find Full Text PDFBackground: In 2012, the Neurocritical Care Society launched a compilation of protocols regarding the core issues that should be addressed within the first hours of neurological emergencies - the (ENLS).
Objective: We aim to evaluate this repercussion through a bibliometric analysis.
Methods: We searched Scopus on October 2022 for articles mentioning ENLS.
Objective: The objective of this study was to analyze the trends in publications on intrathecal baclofen (ITB) therapy.
Methods: We searched Elsevier's Scopus database in February 2022 to find articles focused on ITB therapy. Data extracted included citation count, publication year, author's country and income category, journal and its 5-year impact factor, research type, disease requiring ITB, and target population.
Objective: To evaluate the efficacy of immunotherapy for GTN treatment after methotrexate-resistance or in cases of multiresistant disease, through a systematic review, as well as to present the first 4 Brazilian cases of immunotherapy for GTN treatment.
Methods: Three independent researchers searched five electronic databases (EMBASE, LILACS, Medline, CENTRAL and Web of Science), for relevant articles up to February/2023 (PROSPERO CRD42023401453). The quality assessment was performed using the Newcastle Ottawa scale for case series and case reports.
Objective: The objective of this study was to assess the Author Impact Factor (AIF) as a useful metric and as a complement to the h-index among neurosurgical researchers.
Methods: The 5-year AIF and h-index were compared among 3 groups of researchers: 1) the 100 most prolific of all time within general neurosurgical journals ("Experienced"), 2) the 100 most prolific during the 2015-2019 period within general neurosurgical journals ("Trending Group"), and 3) the 100 postgraduation year 7 neurosurgical residents with the highest h-index ("Amateur").
Results: The Amateur group had a lower median h-index than the Experienced (6 vs.
Background: Clinical Practice Guidelines (CPGs) are invaluable tools to assure evidence-based spine surgery care. In this study, we aimed to identify perceptions, barriers, and potential determinants for the use of CPG among Latin American spine surgeons.
Methods: A 28-item questionnaire regarding the use of CPGs was sent to the members of AO Spine Latin America.
Introduction: The present study aims to investigate whether mothers from Culturally and Linguistically Diverse (CALD) backgrounds present with higher levels of demoralization in comparison with their non-minority counterparts, and to explore potential correlations between demoralization and anxiety as well as depression in the same sample of mothers.
Methods: Women admitted to a public tertiary care teaching hospital were invited to participate in the study within 24-48 hours following delivery. The study compared women who did not regard English as their main spoken language to native English-speaking women.