Publications by authors named "Matheus Gomes Barcelos"
Article Synopsis
- Superinfection inhibition occurs when certain viruses prevent additional viruses from entering infected host cells, ensuring the genetic dominance of the first virus.
- Research has explored this phenomenon in giant amoeba-infecting viruses, specifically mimivirus and moumouvirus, which have shown the ability to inhibit new infections, while megavirus does not.
- The study highlights that mimivirus and moumouvirus disrupt amoebic phagocytosis, altering host cell behavior, whereas megavirus allows continued entry of new virions, indicating significant differences in viral-host interactions despite their evolutionary similarities.
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Exp Biol Med (Maywood)
November 2023
Article Synopsis
- The capsid of a virus plays a crucial role in its life cycle, mainly by protecting its genetic material and facilitating interaction with host cells to promote infection.
- Research has notably focused on giant viruses (GVs) that infect protists, which have unique capsid structures with bacterial-like dimensions and numerous proteins.
- This review highlights the intriguing surface fibrils found on mimivirus capsids, discussing their characteristics, functions, and variations across different nucleocytoviruses.
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