Fluoroquinolone and sulfonamide antibiotics (single and mixtures) impair the motor function of zebrafish larvae at environmentally relevant concentrations.

The occurrence of antibiotics in freshwater is a global concern, with evidence pointing to potential neurotoxic effects after prolonged exposure. However, data on their impact on behavior, particularly at environmentally relevant concentrations, remain limited. This study examined the motor function of zebrafish larvae exposed to single and mixture of antibiotics from the sulfonamide and fluoroquinolone classes.