Upcycling onion peels for enhanced gas barrier and antioxidant bioplastics based on starch from potato processing slurries.

The upcycling of food waste into high-value materials presents a key opportunity for sustainable waste management. While onion peel (OP) extracts have been investigated as additives for bioplastics, this study explores the direct incorporation of whole powdered OP (5-20 wt%) into starch-based films, eliminating extraction steps and fully valorizing this agro-industrial by-product. Using starch recovered from potato processing slurries as the polymeric matrix, the influence of OP on film structure, mechanical performance, water resistance, gas permeability, and antioxidant activity was evaluated.

Hydrogel Bioinks of Alginate and Curcumin-Loaded Cellulose Ester-Based Particles for the Biofabrication of Drug-Releasing Living Tissue Analogs.

3D bioprinting is a versatile technique that allows the fabrication of living tissue analogs through the layer-by-layer deposition of cell-laden biomaterials, viz. bioinks. In this work, composite alginate hydrogel-based bioinks reinforced with curcumin-loaded particles of cellulose esters (CEpCUR) and laden with human keratinocytes (HaCaT) are developed.

Alginate-Lysozyme Nanofibers Hydrogels with Improved Rheological Behavior, Printability and Biological Properties for 3D Bioprinting Applications.

In this study, alginate nanocomposite hydrogel bioinks reinforced with lysozyme nanofibers (LNFs) were developed. Alginate-LNF (A-LNF) suspensions with different LNF contents (1, 5 and 10 wt.%) were prepared and pre-crosslinked with 0.

The proto CpG island methylator phenotype of sessile serrated adenomas/polyps.

Sessile serrated adenomas/polyps (SSA/Ps) are the putative precursors of the ~20% of colon cancers with the CpG island methylator phenotype (CIMP). To investigate the epigenetic phenotype of these precancers, we prospectively collected fresh-tissue samples of 17 SSA/Ps and 15 conventional adenomas (cADNs), each with a matched sample of normal mucosa. Their DNA was subjected to bisulfite next-generation sequencing to assess methylation levels at ~2.