Publications by authors named "Martin Nyberg"
Objective: Disease recurrence, particularly intravesical recurrence (IVR) after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC), is common. We investigated whether violations of onco-surgical principles before or during RNU, collectively referred to as surgical violation (SV), were associated with survival outcomes. Material and methods: Data from a consecutive series of patients who underwent RNU for UTUC 2001-2012 at Skåne University Hospital Lund/Malmö were collected.
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- Limited information exists on lymph node metastases (LNMs) in upper tract urothelial carcinoma (UTUC), prompting a study to analyze their location and complications post-surgery.
- Conducted across multiple Nordic hospitals, the study involved patients with advanced UTUC, who underwent radical nephroureterectomy and lymph node dissection with specific templates for each side.
- Results indicated LNMs in about 23% of patients, with higher rates on the right side, and only a few experienced serious complications within 90 days, suggesting the templates effectively captured most LNMs without significant risks.
Article Synopsis
- - The study examines the clinical presentation and outcomes of 33 patients with suspected urosymphyseal fistula (USF) following pelvic radiotherapy, focusing on diagnostic delays, symptoms, and treatment results over a median follow-up of 22 months.
- - Out of the 24 patients diagnosed with USF, the majority were elderly males, with local pain being the most common symptom, while a significant number faced delays in diagnosis and had complications, including osteomyelitis.
- - The findings suggest that endourologic procedures in patients who have received pelvic radiotherapy should be handled with care due to associated risks and potential complications.
Objective: Differences in outcome after radical prostatectomy for prostate cancer can partly be explained by intersurgeon differences, where degree of experience is one important aspect. This study aims to define the learning curve of robot-assisted laparoscopic prostatectomy (RALP) regarding oncological and functional outcomes.
Materials And Methods: Out of 4003 enrolled patients in the LAPPRO trial, 3583 met the inclusion criteria, of whom 885 were operated on by an open technique.
Background: Radical prostatectomy reduces mortality among patients with localised prostate cancer. Evidence on whether different surgical techniques can affect mortality rates is lacking.
Objective: To evaluate functional and oncological outcomes 8 yr after robot-assisted laparoscopic prostatectomy (RALP) and open retropubic radical prostatectomy (RRP).
Background: Conclusive evidence of superiority in oncological outcome for robot-assisted laparoscopic prostatectomy (RALP) over retropubic radical prostatectomy (RRP) is lacking.
Objective: To compare RALP and RRP regarding recurrent disease and to report the mortality rate 6 yr after surgery.
Design Setting And Participants: A total of 4003 men with localized prostate cancer were enrolled between 2008 and 2011 in Laparoscopic Prostatectomy Robot Open (LAPPRO)- a prospective, controlled, nonrandomized trial performed at 14 Swedish centers.
Objectives: To evaluate how surgeon heterogeneity - the variation in outcomes between individual surgeons - influences functional and oncological outcomes after robot-assisted laparoscopic prostatectomy (RALP) and retropubic radical prostatectomy (RRP), and to assess whether surgeon heterogeneity affects the comparison between RALP and RRP.
Patients And Methods: Laparoscopic Prostatectomy Robot Open (LAPPRO) is a prospective, controlled, non-randomized trial performed at 14 Swedish centres with 68 operating surgeons. A total of 4003 men with localized prostate cancer were enrolled between 2008 and 2011.
Background: The adoption of robot-assisted laparoscopic radical prostatectomy (RALP) has increased rapidly, despite lack of conclusive evidence of its superiority regarding long-term outcomes over open retropubic RP (RRP). In 2015, we reported on 12-mo follow-up from the LAPPRO trial showing a moderate advantage of RALP regarding erectile dysfunction. No significant differences were seen for urinary incontinence or surgical margin status.
View Article and Find Full Text PDFPCA3 as a diagnostic marker for prostate cancer: a validation study on a Swedish patient population.
Scand J Urol Nephrol
December 2010
Objective: Prostate cancer antigen 3 in urine (uPCA3) has been shown to perform better than total prostate-specific antigen in serum (tPSA) to predict prostate cancer (PCa) detection. The aim of this study was to validate the diagnostic precision of uPCA3 in a mixed set of patients with no previous history of PCa, including patients with previous negative biopsies.
Material And Methods: The study included 62 men scheduled for prostate biopsy at Skåne University Hospital Malmö, Sweden.