Publications by authors named "Mark P Ranasinghe"

Article Synopsis
  • - The WHO recommends tailored physical activity guidelines for various countries to better fit the needs of specific underactive populations, including those with chronic conditions, disabilities, and older adults, as these groups face unique barriers to movement.
  • - A scoping review examined physical activity guidelines from multiple countries and regions, analyzing recommendations for the aforementioned populations and identifying deficiencies in alignment with WHO standards.
  • - The review found that many countries lack specific guidelines for individuals with chronic conditions and disabilities, with 46% not providing targeted advice for these groups, resulting in a significant gap in meeting WHO recommendations.
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Background: Acute decompensated heart failure involves a high rate of mortality and complications. Management typically involves a multi-day hospital admission. However, patients often lose part of their function with each successive admission, and are at a high risk for hospital-associated complications such as nosocomial infection.

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Transcatheter aortic valve implantation (TAVI) has emerged as an important alternative to surgical aortic valve repair (SAVR) for patients with severe aortic stenosis. This rapidly advancing field has produced new-generation devices being delivered with small delivery sheaths, embolic protection devices and improved retrieval features. Despite efforts to reduce the rate of thrombotic complications associated with TAVI, valve thrombosis and cerebral ischaemic events post-TAVI continue to be a significant issue.

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