Publications by authors named "Mark D Kiri"
Transepithelial/transendothelial electrical resistance (TEER) is a label-free assay that is commonly used to assess tissue barrier integrity. TEER measurement systems have been embedded in organ-on-a-chip devices to provide live readouts of barrier functionality. Yet, these systems commonly provide the impedance values which correspond to the highest level of permeability throughout the chip and cannot provide localized information on specific regions of interest.
View Article and Find Full Text PDFMesenchymal Stem Cells as a Promising Cell Source for Integration in Novel In Vitro Models.
Biomolecules
September 2020
Article Synopsis
- The relevance of in vitro models for studying human biology relies on using the right human cell source and modeling systems that mimic real human conditions.
- Mesenchymal stem cells (MSCs) are highlighted as a valuable resource due to their ability to differentiate into various cell types without the ethical issues related to other stem cells.
- Advanced platforms like microfluidics, Organs-on-a-Chip, and organoids are enhancing researchers' ability to replicate complex in vivo environments, making these integrated systems significant for clinical and research purposes.