Publications by authors named "Mark D Francisco"

Article Synopsis
  • Sulfonylureas (SUs), like gliclazide and glimepiride, are commonly used medications for managing type 2 diabetes in the Philippines, and the study aimed to explore the genetic factors affecting their effectiveness.
  • The research involved 252 participants across two studies, where genetic testing was conducted to identify associations between genetic variants and the individual responses to these medications.
  • Results showed that certain genetic variants were significantly linked to poor responses to gliclazide and glimepiride, suggesting that understanding these genetic factors could improve treatment strategies for diabetes in the Filipino population.
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Unlabelled: In this study, near-infrared (NIR) technology was utilized to develop a low-cost real-time near infrared (NIR) guiding device for cannulation. A portable device that can be used by medical practitioners and also by students for their skills development training in performing cannulation.

Methods: First, is the development of a reflectance type optical vein finder using three (3) light emitting diode (LED) lights with 960 nm wavelength, complementary metal-oxide-semiconductor-infrared (CMOS-IR) sensor camera with 1920 × 1080 UXGA (1080P), IR filter set for the given wavelength, and an open-source image processing software.

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Article Synopsis
  • Environmental and economic factors are increasing the demand for electric vehicles, necessitating advancements in lithium-ion battery (LIB) separators for mass transportation.
  • This study explores the fabrication of innovative separators using near-field electrospinning (NFES) to create poly(vinylidene fluoride) (PVDF) membranes and a sol-gel method to coat various fabrics.
  • Results show that the newly developed separators demonstrate superior ionic conductivity, porosity, and thermal stability compared to commercial polypropylene separators, marking a significant advancement in LIB technology.
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Diabetes mellitus (DM) is a known risk factor for morbidity and mortality among patients with COVID-19 based on recent studies. While there are many local and international guidelines on inpatient management of diabetes, the complicated pathology of the virus, the use of glucose-elevating drugs such as glucocorticoids, antivirals and even inotropes, and various other unique problems has made the management of in-hospital hyperglycemia among patients with COVID-19 much more difficult than in other infections. The objective of this guidance is to collate and integrate the best available evidence that has been published regarding in-patient management of diabetes among patients with COVID-19.

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Article Synopsis
  • Medical laboratory testing often requires venous blood samples, which can be painful and difficult to collect due to the challenges of locating suitable veins.
  • The paper reviews various low-cost vein finder prototypes that utilize near-infrared (NIR) light technology to improve the accuracy of venous access and reduce discomfort for patients.
  • Despite some advancements, the development of these prototypes still faces challenges, such as limited human testing, variations in methodologies, and the need for more comprehensive assessments of phlebotomist performance when using these devices.
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