Publications by authors named "Mariya Gennadevna Nikolaeva"

Background: The risk of late recurrence after venous thromboembolism (VTE) related to weak transient risk factors (RFs) in young women guides thromboprophylaxis.

Objective: To estimate the incidence of recurring VTE in untreated women with a first episode due to combined oral contraceptives (COCs), pregnancy-puerperium, minor trauma-fracture, brief surgery, infection or brief immobility.

Methods: We performed a multicentre, international, observational, retrospective study on women aged 18-55 years old, free from high-risk thrombophilia and subsequently monitored.

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Background:  In young women with venous thromboembolism (VTE) related to weak transient risk factors, it remains unknown whether stress levels and intimate partner violence (IPV) are associated with recurrence. The VTE-WEAK study aims to investigate the association between perceived stress and IPV with a recurrence of VTE in women with a first episode of VTE due to combined oral contraceptives, pregnancy-puerperium, minor trauma/fracture, brief surgery, infection or brief immobility, and not using antithrombotic prophylaxis.

Material And Methods:  We performed a multicenter, international, observational, retrospective study on women referred for thrombophilia screening who were subsequently monitored.

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Background: Intimate partner violence (IPV) targeting women is probably underestimated during a woman's lifetime. Venous thromboembolism (VTE) is a multifactorial disease associated with haemostasis-activating conditions. Minor injuries can trigger VTE.

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Article Synopsis
  • This report discusses 20 cases where young women experienced first VTE events linked to intimate partner violence, often with other risk factors involved.
  • Many women did not disclose their experiences of violence during consultations, indicating that intimate partner abuse may be commonly overlooked and suggesting a need for systematic screening in healthcare settings.
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Introduction: Limitations in the data used to define thromboprophylaxis for patients with antiphospholipid antibodies (aPLAbs) and thrombosis include uncertainties after an initial provoked venous thromboembolic event (VTE). We aimed to study such cases associated with combined oral contraceptive (COC) intake.

Methods: We retrospectively analysed thrombotic outcomes after a first COC-associated VTE and positive aPLAbs, with a low risk HERDOO2 score, on low-dose aspirin (LDA) secondary thromboprophylaxis, seen from 2010 to 2021 in 3 tertiary referral centres, one in France and 2 in Russia.

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