Publications by authors named "Marion Delaune"
Serious infections in patients with VEXAS syndrome: data from the French VEXAS registry.
Ann Rheum Dis
February 2024
Article Synopsis
- VEXAS syndrome is a poorly understood, acquired autoinflammatory disease linked to serious infections, highlighting significant risks for susceptible patients.
- A study of 74 patients revealed that the most frequent infection sites were the lungs, skin, and urinary tract, with a notable microbiological confirmation rate.
- Key risk factors for serious infections included age over 75, specific genetic mutations, and treatment with JAK inhibitors, with 36% of patients dying during the study, often due to these severe infections.