Concordance between creatinine- and cystatin C-based eGFR in clinical practice.

The mean of GFR-estimates based on serum creatinine (eGFR) and cystatin C (eGFR) has superior accuracy than each estimate alone. Recent studies have shown that agreement between eGFR and eGFR is an indicator for the accuracy of the mean of the two estimates. As long as the difference between the two (|ΔeGFR|) is below 40%, a high P accuracy rate of more than 90% was documented in research settings using gold-standard GFR measurements.