Optimization of essential oil combinations for enhanced antibacterial properties using mixture design methodology.

This study investigated the synergistic antibacterial potential of combining essential oils (EOs) from origanum, rosemary, and pepper using mixture design methodology. The EOs were extracted and analyzed by GC/MS, and their major compounds were identified as carvacrol, 1,8-cineole, and β-caryophyllene, respectively. A simplex-centroid mixture design was employed to optimize the EO combinations for enhanced antibacterial activity against pathogenic bacteria.

Essential Oil Stabilisation by Response Surface Methodology (RSM): Nanoemulsion Formulation, Physicochemical, Microbiological, and Sensory Investigations.

This manuscript aimed to optimise the encapsulation of essential oil into nanoemulsion. Response Surface Methodology results were best fitted into polynomial models with regression coefficient values of more than 0.95.