Publications by authors named "Marcin Zytkiewicz"

Article Synopsis
  • - Brugada phenocopy (BrP) is characterized by a Brugada-like ECG pattern and can occur due to various conditions, but it doesn't increase the risk of serious heart issues like Brugada syndrome (BrS) does.
  • - A case is presented of a 69-year-old woman with moderate hyponatremia who exhibited a saddle-back ST-segment elevation on her ECG, which was linked to her liver metastases compressing her heart.
  • - The ECG changes resolved quickly after treating her hyponatremia with sodium chloride, demonstrating that even mild electrolyte imbalances can lead to BrP when compounded by other factors like mechanical heart compression.
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Blunt chest trauma (BCT) may rarely trigger stress-induced takotsubo syndrome (TTS) which requires dif f erential diagnosis with myocardial contusion and BCT-induced myocardial infarction. So far reported cases have been presented as apical ballooning or inverted (reverse) TTS forms but not as a midventricular variant. The authors described a case of a 53-year-old female admitted to Intensive Care Unit after motor vehicle accident with BCT and airbag deployment during car roll over.

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Shark fin or triangular QRS-ST-T waveform ECG pattern, also known as lambda-wave ST elevation or giant R wave syndrome, is a particular ECG presentation where QRS complex, ST-segment and T-wave are fused in a unique complex. Originally described in some patients with ST-segment elevation myocardial infarction (STEMI) during the acute phase, it has been found to be associated with a high risk of ventricular fibrillation and cardiogenic shock as well as with a high in-hospital mortality. However, shark fin ECG pattern has also been reported in patients with non-acute coronary syndrome related ST-elevation (NASTEP), including stress-induced takotsubo syndrome (TTS).

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Mechanical heart compression, including that from mediastinal tumor, may cause Brugada-like ECG pattern. Such ECG pattern might also be observed in intracardiac tumor obstructing the right ventricular out"ow tract (RVOT). Eight cases with Brugada-like ECG and tumors involving RVOT have been described so far; 4 growing in the mediastinum (with one example of in"ammatory mass), 3 with intracardiac location, and 1 being an organized pericardial hematoma.

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Brugada syndrome (BrS) is an inherited channelopathy characterized on ECG by coved (type 1) or saddle-back (type 2) ST-segment elevation (STE) of 2 or more mm in the right precordial leads and is associated with an increased risk of malignant ventricular arrhythmias. The term Brugada phenocopy (BrPh) indicates conditions that may reversibly induce Brugada-like ECG pattern in patients without true BrS; e.g.

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Native heart valve thrombosis (NHVT) is a rare valvular pathology, usually associated with prothrombotic state or disturbed intracardiac blood flow related to structural valve abnormalities. While different venous and arterial thromboembolic complications of COVID-19 have been widely described, so far NHVT has not been reported in the context of the disease. The authors describe 4 cases of NHVT associated with COVID-19, revealed on aortic, mitral (2 patients) and tricuspid valve.

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Article Synopsis
  • - Arterial thromboembolic events (ATE), like venous thromboembolism, are primarily seen in severely ill COVID-19 patients and can lead to serious complications involving the brain, heart, aorta, and limbs.
  • - A case study details a 53-year-old man with Duhring disease and severe COVID-19 pneumonia who developed total occlusion of the right superficial femoral artery despite receiving anticoagulation therapy and other medications.
  • - The patient ultimately faced unfavorable outcomes due to respiratory failure, highlighting that ATE can occur even in patients on anticoagulants and suggesting further investigation into the risks associated with certain COVID-19 treatments like JAK inhibitors.
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Although Slavic populations account for over 4.5% of world inhabitants, no centralised, open-source reference database of genetic variation of any Slavic population exists to date. Such data are crucial for clinical genetics, biomedical research, as well as archeological and historical studies.

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Unlabelled: COVID-19 patients, particularly those with severe pulmonary involvement, are at an increased thromboembolic risk related, among various causes, to the cytokine storm and excessive activation of the coagulation cascade and platelets. Different intensity of anticoagulation for them is proposed, mainly with low molecular weight heparins (LMWHs); in a confirmed pulmonary embolism (PE) the therapeutic dose of LMWH is routinely used. Some authors suggest that hemorrhagic complications in COVID-19 patients are rare.

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Unlabelled: Coronavirus disease-2019 (COVID-19) and legionnaires disease (LD) caused by Gram-negative water-born bacteria Legionella pneumophila show certain similarities, including a predisposition to pulmonary involvement and extrapulmonary manifestations in some of the patients infected. One disease can mimic the other, both can rarely coexist.

Case Series Report: The authors describe 7 such cases (5 females), aged 51-90 years (mean 69.

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Unlabelled: Cardiovascular complications of the COVID-19 comprise cardiac arrhythmias, including sinus bradycardia (SB).

Case Reports: The authors present clinical data of 19 hospitalized patients (12 males), aged 20-73 years, with marked (less than 45/min during daily hours) self-limiting SB. None of them had SB at admission or earlier, none had used cardiovascular medications potentially decreasing the heart rate.

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In the course of COVID-19 pandemic, many patients with diagnosed or suspected disease do require echocardiography. At the same time, when it comes to the echocardiographers, there is a fear of their being exposed to contamination. At COVID-19-dedicated hospital examinations are bedside, and in some patients hand-held or tablet-based echocardiography should be preferred; the echocardiographer routinely puts on a complete protective uniform.

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The associations between depression and coronary heart disease, especially via platelet hyperactivity, have been widely described. The relationships between depression and venous thromboembolism are less clear. We present three cases of pulmonary embolism (PE) in patients with previously diagnosed depression and discuss possible, depression-related prothrombotic factors, including the impact of psychotropic drugs.

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Immobility due to sitting position during traveling is a well-known risk factor for venous thromboembolism (VTE). Beasley et al. (2003) first proposed the name "eThrombosis" for a case in which VTE was related to prolonged seated immobility at computer.

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Introduction: Acetylsalicylic acid (ASA) due to its antiplatelet action is used in ischemic stroke therapy. The platelet response to ASA shows an interindividual variation. Decreased platelet sensitivity to ASA is termed as resistance to ASA.

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