Radial versus femoral access in ST-elevation myocardial infarction complicated by out of hospital cardiac arrest.

Background: Out of hospital cardiac arrest (OHCA) is the most concerning complication of ST-elevation myocardial infarction (STEMI) and is associated with a poor prognosis. Immediate coronary angiography (CAG) and primary percutaneous coronary intervention (PCI) are recommended to restore myocardial perfusion. However, there is limited data on the preferred vascular access for these patients, who are at higher risk of both hemorrhagic and thrombotic events.

Psychoactive substance use in elderly patients: Insights from the addiction in intensive cardiac care units (ADDICT-ICCU) study.

Background: The United Nations has recently highlighted a global epidemic of psychoactive substance use among elderly people. Although several studies have established the important prognostic impact of psychoactive substance use in terms of cardiovascular events, the epidemiological characteristics of this consumption in elderly patients hospitalized in intensive cardiac care units (ICCUs) are not well established.

Aim: To assess the prevalence of psychoactive substance use in all consecutive elderly patients hospitalized in ICCUs from the Addiction in Intensive Cardiac Care Units (ADDICT-ICCU) trial.

Prevalence of recreational drug use in myocardial infarction patients without standard modifiable risk factors: Insights from a multicenter prospective cohort study.

Background: The prevalence of recreational drug use in myocardial infarction (MI) patients without standard modifiable cardiovascular risk factors (SMuRF) namely hypercholesterolemia, hypertension, diabetes and smoking, remains unknown.

Methods: All patients enrolled in The Addiction in Intensive Cardiac Care Units (ADDICT-ICCU) study, a French multicenter prospective observational study which systematically assessed the use of recreational drug within 2 h of admission, and presenting with MI but without known coronary artery disease were included. We compared patients with and without SMuRF.

Risk Factors and Clinical Outcomes of Asymptomatic Bacteriuria in Pregnant Women: A Comprehensive Analysis.

Background Asymptomatic bacteriuria (ASB) in pregnant women poses risks to maternal and neonatal health. Understanding its prevalence and associated risk factors is crucial for effective management. This study aimed to determine the prevalence of ASB among pregnant women and identify associated risk factors.

Pathways in permanganate oxidation of mandelic acid: reactivity and selectivity of intermediate manganese species.

We report a comprehensive kinetic and product study of the oxidation of mandelic acid (MA) by permanganate in the pH range of 1-13, including a full account of total oxidizing equivalents (five and three-electron change in acidic and basic media, respectively). In the entire pH range, the reaction shows a primary kinetic deuterium isotope effect (/ ≥8-9), indicating rate-limiting hydride transfer. The deuterium label in α-deutero-mandelic acid is retained in benzaldehyde.

[Recreative drug use and cardiovascular disease].

Widely spread, and continuously increasing, recreational drug use in general population has been associated with cardiovascular events, as illustrated by clinical studies and supported by a pathophysiological rationale. Understanding the cardiovascular effects of drugs, screening, and secondary prevention are crucial components in the management of those patients in cardiology.

A review of potential mechanisms and uses of SGLT2 inhibitors in ischemia-reperfusion phenomena.

Recently added to the therapeutic arsenal against chronic heart failure as a first intention drug, the antidiabetic drug-class sodium-glucose cotransporter-2 inhibitors (SGLT2i) showed efficacy in decreasing overall mortality, hospitalization, and sudden death in patients of this very population, in whom chronic or acute ischemia count among the first cause. Remarkably, this benefit was observed independently from diabetic status, and benefited both preserved and altered ventricular ejection fraction. This feature, observed in several large randomized controlled trials, suggests additional effects from SGLT2i beyond isolated glycemia control.

Fluoride Geochemistry and Exposure Risk Through Groundwater Sources in Northeastern Parts of Rajasthan, India.

Exposure to fluoride concentrations above a threshold of 1.5 mg/L can cause joint pains, restricted mobility, skeletal and dental fluorosis. This study aims to determine the hydrochemical evolution of the fluoride-rich groundwater and estimate the risk of fluoride exposure to the residents of semi-arid northeastern part of Rajasthan, India.

Pressure Pain Threshold in Patients With Chronic Pain: A Systematic Review and Meta-Analysis.

Introduction: In chronic pain conditions, the pressure pain threshold has been used to investigate the presence of central sensitization.

Methods: A systematic review and meta-analysis were conducted to compare the threshold in chronic pain patients and healthy individuals. Ovid MEDLINE and Embase up to July 2019 were used to conduct the search.

An insight into the awareness and utilization of "dental evidence" among the police force in Punjab.

Introduction: The prime objective of the subsequent investigation is to ascertain the identity of an individual by the evaluation of evidence and facts relevant to crime or disaster. The whole process revolves around the correct interpretation of the facts, reconstruction, and comprehension of the sequence of events and thus single evidence forms a very important piece of information. In most of the countries including India, forensic medical, and dental evaluation at the crime scene are performed by police officials as medical and dental experts are rarely involved as first responders.

Nontraditional cardiovascular biomarkers and estimation of cardiovascular risk in predialysis chronic kidney disease patients and their correlations with carotid intima media thickness.

Background: Cardiovascular biomarkers such as N-terminal pro-B-type natriuretic peptide (NT-proBNP), cardiac troponin T (cTnT), hs-CRP (high sensitivity C-reactive protein), and albuminuria predict underlying heart disease in the general population as well as CKD patients.

Objectives: We aimed to study the association of NT-proBNP, cTnT, hs-CRP, and spot urine albumin creatinine ratio with carotid intima media thickness (CIMT) for cardiovascular risk estimation in predialysis CKD (chronic kidney disease) patients.

Patients And Methods: This cross-sectional study included a total of 120 adult predialysis CKD patients.

Optically stimulated luminescence (OSL) response of Al2O3:C, BaFCl:Eu and K2Ca2(SO4)3:Eu phosphors.

This paper investigates the optically stimulated luminescence (OSL) response of BaFCl:Eu and K2Ca2(SO4)3:Eu phosphors for different doses and bleaching durations. The results have also been compared with the commercially available Landauer Al2O3:C (Luxel®) dosemeter. Nanocrystalline K2Ca2(SO4)3:Eu is known to be a sensitive thermoluminescent phosphor, but its OSL response is hardly reported.