Publications by authors named "Manjunath G N"

Background: Red cell distribution width (RDW) is an emerging biomarker associated with systemic inflammation, nutritional status, and prognosis in various cancers. However, its correlation with treatment-related toxicities such as mucositis and weight loss in head and neck cancer patients undergoing radiotherapy remains underexplored.

Objective: This study aimed to evaluate the correlation between RDW (pre-treatment, post-treatment, and delta) with weight loss and mucositis severity in patients who received head and neck radiotherapy, with or without concurrent chemotherapy.

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This case study discusses how a month-long, personalized yoga therapy program impacted a 57-year-old woman with lung cancer that had spread to her brain, who is currently receiving palliative care. Her yoga routine included gentle exercises (Sukshma Vyayama), breathing techniques (Pranayama), and meditation, which were suitable to fit her physical abilities. The Functional Assessment of Cancer Therapy-Lung (FACT-L) scale was used to measure her quality of life, revealing significant improvements in her well-being.

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Introduction Head and neck cancers account for 30% of malignancies in India and oral squamous cell carcinoma is most common. 80% of the patients present with locally advanced disease and many of them are inoperable. In this study we documented the outcomes of neoadjuvant chemotherapy (NACT) in locally advanced oral cancer staged T4 with regards to downstaging the disease and to make the tumor more amenable for surgery with better access.

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Article Synopsis
  • Testicular cancers, like embryonal cell carcinoma, rarely spread to the heart, but when they do, it usually indicates widespread disease.
  • A 28-year-old man experienced cardiac metastasis from his testicular cancer, but his symptoms improved following chemotherapy.
  • It's crucial for healthcare providers to maintain a high suspicion for heart issues in patients with chest symptoms and to involve cardiologists early for better treatment outcomes.
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Introduction Cervical cancer might intensify the psychological distress among patients with cervical cancer and the distress caused by the diagnosis and treatment. So, depression and anxiety are at higher levels in patients with cervical cancer. Yoga Nidra and Pranayama are thought to reduce the aftereffects of chemotherapy and radiotherapy potentially.

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Oral cancers comprise 50% of all head and neck malignancies in India which can be attributed to tobacco chewing. Advanced oral cancers are managed with surgery followed by adjuvant radiotherapy or adjuvant chemoradiation. There is paucity of studies regarding need for adjuvant treatment in oral cancers with close margins i.

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Background: Contraceptive information and services are fundamental to the health and human rights of all individuals. Low contraceptive use is a major challenge faced in India. To determine whether a lack of awareness of contraceptive methods was a factor, we assessed the perception of women on contraceptive methods, their safety and efficacy and further determined whether their demographic background played any role in their perception.

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Verrucous carcinoma of oral cavity is a highly well differentiated variant of squamous cell carcinoma with a low potential for invasion and metastasis. It is prevalent in the tobacco quid chewing population in our region. In this observational study, we reviewed the medical case records of 58 patients treated for oral verrucous carcinoma staged T2 to T4a.

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Locally advanced oral cancers extending to infratemporal fossa (ITF) are a challenge to head and neck surgeons. These tumors are classified as T whenever the masticator space (MS), pterygoid muscles (PM), and pterygoid plates (PP) are involved according to AJCC classification. Until recently, these tumors were considered inoperable and treated only with palliative intent.

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Purpose: To quantify and compare dose-volume and dose-length parameters of cervical esophagus between three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiation therapy (IMRT) and to correlate with incidence of cervical strictures in head and neck cancer irradiation with radical intent.

Materials And Methods: Forty consecutive head and neck cancer patients who received radical radiation therapy, either with 3DCRT (n = 20) or IMRT (n = 20), between December 2011 and August 2012 were retrospectively analyzed and followed up for at least 4 years post-treatment completion.

Results: The volumes of cervical esophagus receiving ≥54 Gy (V54) and ≥60 Gy (V60) and lengths receiving circumferential dose of ≥50 Gy (L50) and ≥54 Gy (L54) were significantly higher in patients treated with IMRT as compared to 3DCRT (P ≤ .

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