Publications by authors named "Manjula D Kasoji"
MicroRNA expression in mice infected with seasonal H1N1, swine H1N1 or highly pathogenic H5N1.
J Med Microbiol
September 2014
Influenza virus infections in humans remain a healthcare concern, and the need for vaccines, therapeutics and prophylactics remains a high priority. Understanding the molecular events associated with influenza-virus-induced pathology may lead to the identification of clinical disease biomarkers and novel antiviral targets. MicroRNAs (miRNAs) are well-conserved endogenous non-coding RNAs known to regulate post-transcriptional gene expression as well as play a major role in many biological processes and pathways.
View Article and Find Full Text PDFShort-read, high-throughput sequencing technology for STR genotyping.
Biotech Rapid Dispatches
April 2012
Article Synopsis
- DNA identification mainly uses short tandem repeat (STR) genotyping but traditional methods have low throughput and lack sequence information.
- High-throughput sequencing technology holds potential for better accuracy in human identification but is not yet validated for forensic use.
- This study outlines a method using high-throughput sequencing to analyze CODIS STR loci, showing it can accurately genotype individuals and mixtures, requiring only 18,500 reads for reliable results while also identifying SNPs and quantifying mixed samples.