Background Biotin, a vital cofactor for carboxylase enzymes, plays a key role in metabolic processes, while silica is believed to support collagen synthesis, contributing to improved skin and hair health. This study investigates the dermatological benefits of standardized plant-based supplements formulated with biotin derived from and a biotin-silica blend extracted from Methods A randomized, double-blind, placebo-controlled clinical trial enrolled 105 participants, with 97 completing the 90-day study. Participants received either Treatment A (placebo), Treatment B (botanical extract of standardised for biotin, 1.
View Article and Find Full Text PDFThe cooling sensation imparted by topical rinse-off formulations, such as facial cleansers, represents a critical sensorial attribute influencing consumer perception and product acceptability. Despite its subjective nature, this effect can be objectively quantified using non-invasive tools such as infrared (IR) thermography and non-contact infrared thermometry. The aim was to develop and internally standardize a reproducible methodology for assessing the immediate cooling effect of rinse-off facial products using IR thermal imaging and non-contact infrared temperature measurement.
View Article and Find Full Text PDFIntroduction Alopecia is a common condition marked by progressive hair loss, influenced by aging, genetics, hormones, and environmental factors. It affects individuals of all ages, often impacting self-esteem and quality of life. Rosemary and lavender oils have gained attention for their antioxidant, anti-inflammatory, and antimicrobial properties, promoting scalp health, follicular stimulation, and hair regrowth.
View Article and Find Full Text PDFIntroduction Androgenetic alopecia (AGA) is a prevalent and progressive hair disorder affecting both men and women. It is characterized by the miniaturization of hair follicles, reduced hair density, and alterations in scalp conditions. Accurate assessment of hair growth parameters is crucial for understanding the progression of AGA and evaluating the efficacy of treatment interventions.
View Article and Find Full Text PDFBackground and objective Scalp dandruff, a prevalent dermatological condition marked by flaking and itching, affects a large segment of the population. Sun exposure, genetics, and dryness, along with winter conditions, indoor heating, and hard water, all contribute to moisture loss and scalp imbalance. This study aimed to evaluate the safety, efficacy, and tolerability of a novel regimen combining a scalp scrub with hydroxy acid derivatives for exfoliation and dandruff removal, and a serum containing copper tripeptide-1, witch hazel (, hesperidin, hyaluronic acid, and pea protein () for hydration and scalp health.
View Article and Find Full Text PDFIntroduction Acne is a common inflammatory condition characterized by comedones, papules, and pustules, often resulting from increased sebum production influenced by hormones such as insulin-like growth factor-1 and androgens. Factors like , medications, sun exposure, cosmetics, and genetics exacerbate acne. This study aims to assess the safety and effectiveness of a novel acne treatment regimen, including a cleanser and serum containing Diacnemide™ (manufactured by Beaucience India Private Limited, Faridabad, India), in improving acne symptoms in adults.
View Article and Find Full Text PDFIntroduction Scalp dandruff is a common dermatological condition characterized by flaking and itching of the scalp, affecting a significant portion of the population. Effective assessment methods are crucial for evaluating treatment outcomes. This study aimed to establish the reliability and correlation of three assessment techniques: Adherent Scalp Flaking Score (ASFS), phototrichogram using CASLite Nova, and the 60-second hair combing test.
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