Antibody response to mycobacterial Rpf B protein and its immunodominant peptides in HIV-TB co-infected individuals.

Diagnosis of TB at early stages of HIV infection may lead to timely intervention for improving patient outcome. Antibodies to Mycobacterium tuberculosis recombinant RpfB protein and two immunodominant peptides of Rpf B protein were evaluated in the sera of HIV TB, HIV and HIV pulmonary TB patients by ELISA. Serum antibodies from 90 % and 65 % of HIVTB patients reacted to recombinant RpfB protein and synthetic peptide RpfP1 respectively.

The continuum of liver injury with severity of dengue fever: A retrospective observational study.

Background: Dengue is a major international health concern prevalent in tropical and sub-tropical countries. There are a paucity of studies on the relationship of hepatic complications with inflammatory parameters in dengue infection.

Methods: Single-centre observational study was conducted at the tertiary care centre in North India.

Analysis of differential expression of protease-activated receptors in patients with allergic fungal rhinosinusitis.

Background: Ever since its characterization in the 1970s, allergic fungal rhinosinusitis (AFRS) has been the subject of much controversy, especially regarding its pathogenesis. In this study, we analyzed the differential expression of genes that encode protease-activated receptors (PAR) in patients with AFRS and patients with chronic rhinosinusitis, and tried to understand the pathogenic basis of this disease.

Objective: To analyze the differential expression of PAR genes in patients with AFRS and in patients with chronic rhinosinusitis.