Novel inhibitory effect of Omega-3 fatty acids regulating pancreatic cancer progression.

Pancreatic cancer is a devastating malignancy in great need of new and more effective treatment approaches. In recent years, studies have indicated that nutritional interventions, particularly nutraceuticals, may provide novel avenues to modulate cancer progression. Here, our study characterizes the impact of ω-3 polyunsaturated fatty acids, eicosapentaenoic acid, and docosahexaenoic acid, as a nutraceutical intervention in pancreatic cancer using a genetically engineered mouse model driven by KrasG12D and Trp53R172H.

[Determination of some oxidative stress, functional and immunological markers in the saliva of patients undergoing bone marrow transplantation (BMT).].

Objective: High doses of chemotherapy used prior to bone marrow transplantation (BMT) promote severe changes in the stomatognathic system. The objective of the present work consisted in evaluating some functional, immunological and oxidative stress markers in saliva of these patients.

Methods: A longitudinal observational study was carried out on 22 patients admitted to the Bone Marrow Transplant Unit of the Oncohematology Service of the Sanatorio Allende between March 2019 and February 2020.

[Effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma].

Introduction: the causative factors of oral squamous cell carcinoma are not necessary and not sufficient causes, even the most accepted ones, such as tobacco and alcohol. Little is known about the cumulative effect of all risk factors for oral cancer. The objective of this work was to analyze whether the sum of oral cancer risk factors is associated with an increase in its risk.

Characterization of Chronic Mechanical Irritation in Oral Cancer.

. Oral mucosa could host many lesions originated by chronic mechanical irritation (CMI) from teeth or dentures, and it has been proposed as risk factor for oral cancer. Nevertheless, the features of CMI factors in oral cancer and other lesions are not assessed.

Characterization of maxillary central incisor: novel crown-root relationships.

Objectives: The periodontal biotype includes crown features of the maxillary central incisor (MCI), whereas root measures have been less studied. The aim of our study was to morphologically characterize MCI and search relationships between crown and root measures.

Material And Methods: One hundred-fifty MCIs were used.

Human temporomandibular joint disc: anatomy and measurements in prenatal development.

The objective of this study was to determine morphological characteristics and measurements of the temporomandibular joint (TMJ) disc in human fetuses between 16 and 20 weeks of intrauterine life, and correlate it with oral-facial neuro-muscular maturing. Scanner images were used to record the length of the disc (D) and the thickness of its anterior middle and posterior bands in TMJ anteroposterior vertical sections from human fetuses of 16, 18 and 20 weeks of intrauterine life (WIL). Mean disc length was 1.

Alterations of the oral ecosystem in children with celiac disease.

Unlabelled: The aim of this work is to evaluate the alterations of the oral ecosystem in symptomatic children with celiac disease (CD), to establish a particular pattern of oral markers that can be used as presumptive diagnosis of CD.

Material & Methods: A sample of n=52 children with CD diagnosis according to the modified criteria of the European Society of Pediatric Gastroenterology and Nutrition (ESPGAN), 1990, was studied. A dental clinical evaluation of soft and hard tissues was performed.

Oral health and salivary factors in rural schoolchildren.

The aim of the present study was to assess the association between some salivary factors and the oral health status of rural schoolchildren of Córdoba (Argentina). The study involved 19 students (aged 5-14 years) who attended 8 rural schools of the region. We determined indices (r)dmf-t, (r)DMF-T and S-OHI.