Association of Dietary Micronutrient Intake and the Metabolome in Children with Chronic Kidney Disease.

Background: Children with chronic kidney disease (CKD) experience poor growth and development via multiple mechanisms. We aimed to describe deficiencies in dietary micronutrient intake and associate dietary micronutrient intake with metabolic pathways.

Methods: The Chronic Kidney Disease in Children cohort study enrolled participants six months to 16 years with CKD stage 2-4 across North America.

Metabolomic signatures of hypocaloric dietary interventions associate with breast cancer risk in the Nurses' Health Study II.

Background: An individual's metabolic state plays a critical role in breast cancer (BC) risk, influenced by factors such as obesity and insulin signaling. Hypocaloric diets induce metabolic changes that influence these metabolic factors, thereby potentially influencing BC risk. However, it remains unclear whether metabolic profiles like those induced by such beneficial diets are associated with BC risk.

Clinical and surgical profiles of patients submitted to plastic surgery procedures after bariatric surgery in a public hospital in Brazil's Midwest.

Introduction: Patients who undergo to gastroplasty present massive weight loss and the plastic surgery represents an important play in the treatment. The aim of this study is to present the profile of patients who underwent plastic surgery after bariatric surgery performed at the Reference Public Hospital in West-Center of Brazil.

Methods: A descriptive, analytical and retrospective study was performed in a single public hospital on patients who underwent post-bariatric plastic surgery from January 2011 to December 2023.

Advancing insights into psoriasis: from pathogenesis to current and emerging therapies.

Psoriasis is a chronic, immune-mediated skin disease, with Plaque Psoriasis being its most common form. It is characterized by well-defined red plaques with raised white crusts. While its pathogenesis remains complex, involving keratinocytes, inflammatory cells and both adaptive and innate immunity, studies have highlighted an association with genetic predisposition.

Randomized clinical trial of photobiomodulation and glass ionomer sealant for hypersensitivity in molar incisor hypomineralization.

This study evaluated the impact of photobiomodulation (PBM) combined with glass ionomer sealant on hypersensitivity, oral hygiene, and sealant retention in molars affected by molar incisor hypomineralization (MIH). Forty-nine children (6-12 years) with MIH (Grade 3, 4a, or 4b) per MIH-TNI criteria were randomly assigned to two groups: control (n = 25, fluoride toothpaste, sealant with self-curing glass ionomer cement, simulated PBM) and treatment (n = 24, fluoride toothpaste, sealant with self-curing glass ionomer cement, active PBM). Hypersensitivity (SCASS, VAS), oral hygiene (OHI-S), and sealant retention (CCC system) were assessed.