Prevalence and Antimicrobial Resistance Patterns of Escherichia coli Isolated From Broiler Chickens in Sylhet District of Bangladesh.

The emergence of antimicrobial resistance (AMR) Escherichia coli in poultry farming is a growing global public health concern, particularly in Bangladesh, where the use of antibiotics remains largely unregulated. This study aimed to determine the prevalence and AMR patterns of E. coli isolated from broiler chickens in Sylhet district of Bangladesh and to investigate the network of coexisting resistance traits among the isolates.

ResLysEmbed: a ResNet-based framework for succinylated lysine residue prediction using sequence and language model embeddings.

Motivation: Lysine (K) succinylation is a crucial post-translational modification involved in cellular homeostasis and metabolism, and has been linked to several diseases in recent research. Despite its emerging importance, current computational methods are limited in performance for predicting succinylation sites.

Results: We propose ResLysEmbed, a novel ResNet-based architecture that combines traditional word embeddings with per-residue embeddings from protein language models for succinylation site prediction.

Medical Artificial Intelligence: Opportunities and Challenges In Infectious Disease Management.

Globally, millions of individuals suffer from infectious diseases, which are major public health concerns caused by bacteria, fungi, viruses, or parasites. These diseases can be transmitted directly or indirectly from person to person, potentially leading to a pandemic or epidemic. Several advancements have been made in molecular genetics for infectious disease management, which include pharmaceutical chemistry, medicine, and infection tracking; however, these advancements still lack control over human infections.

Chronic kidney disease and incident cancer risk: an individual participant data meta-analysis.

Background: Studies examining the association of chronic kidney disease (CKD) with cancer risk have demonstrated conflicting results.

Methods: This was an individual participant data meta-analysis including 54 international cohorts contributing to the CKD Prognosis Consortium. Included cohorts had data on albuminuria [urine albumin-to-creatinine ratio (ACR)], estimated glomerular filtration rate (eGFR), overall and site-specific cancer incidence, and established risk factors for cancer.

The deadly drink: Nipah virus transmission through date palm sap, cultural practices and the evolution of behavioral interventions in Bangladesh over two decades.

Nipah virus (NiV) has emerged as a significant public health threat, with recurring outbreaks in Bangladesh often linked to the consumption of raw date palm sap contaminated by fruit bats (Pteropus species). Over the past two decades, substantial efforts have been made to understand the cultural context of sap consumption, promoting behavior change and developing interventions to prevent NiV spillover. Despite these efforts, achieving sustainable change in sap consumption practices remains challenging due to deep-seated cultural practices, community perceptions of sap consumption, habitual behaviors, limited awareness of health risks and economic barriers.