Publications by authors named "M R Mathis"
Objective: To investigate whether non-adherence to the combined Infectious Disease Society of America (IDSA), the Surgical Infection Society (SIS), and the Society for Healthcare Epidemiology of America (SHEA) guideline based antibiotic choice, timing, and/or dose of vancomycin was associated with Surgical Site infections in surgeries where vancomycin was administered.
Summary Background Data: Despite the pivotal role of antibiotics in preventing surgical site infections (SSIs), widespread non-adherence to IDSA/SIS/SHEA guidelines especially related to vancomycin for intraoperative antibiotic prophylaxis continues. It is unclear whether this non-adherence is associated with SSIs.
Introduction: Unnecessary preoperative testing before low-risk surgery contributes to excess healthcare costs, care cascades, and surgical delays. The Right-Sizing Testing Before Elective Surgery intervention is a multilevel, multicomponent intervention piloted at three hospital sites to reduce low-value testing. To understand how the de-implementation strategies could be tailored across diverse healthcare settings, we applied the Framework for Reporting Adaptations and Modifications to Evidence-Based Implementation Strategies (FRAME-IS) to track site-specific modifications.
View Article and Find Full Text PDFBackground: Cardiogenic shock has significant associated morbidity and mortality with a wide range of vasoactive management strategies. However, the extent to which variation in vasoactive and inodilator therapies is explained by patient level variables versus clinical practice variation remains underexplored.
Methods: The cohort included 4,525 patients admitted to ICUs at Michigan Medicine from 01/01/2014-12/31/2023 diagnosed with cardiogenic shock identified by billing codes.