Neurotoxic and some systemic effects of cadmium oxide nanoparticles following their subchronic intranasal administration to rats: experimental data analysis.

Industrial emissions of cadmium, which is used in various industries, and formation of cadmium nanoparticles during high-temperature technological processes aggravate the problem of chemical pollution. Insufficient understanding of the toxic impact of cadmium nanoparticles, coupled with the serious multisystem toxicity of this metal, necessitate expansion of knowledge about their potential toxic effects. We assessed the response of female outbred albino rats to subchronic exposure to cadmium oxide nanoparticles (CdO NPs) administered intranasally at the concentration of 0.

Molecular basis of cadmium Cardiotoxicity: Chamber-Specific effects of CdO nanoparticles and soluble CdCl exposure.

Cadmium, a pervasive xenobiotic, contributes to cardiovascular morbidity and mortality. We investigated the molecular mechanisms of cadmium's impact on the myocardium of various heart chambers. Outbred male rats received 18 intraperitoneal injections of CdCl solution (0.

Nano-assault on the heart: Molecular pathways of lead oxide nanoparticle cardiotoxicity.

Lead is closely associated with increased cardiovascular risk. We investigated the molecular mechanisms underlying the impact of lead nanoparticle exposure (Pb) on the myocardium in different heart chambers, comparing the effects of Pb to those of its soluble form. Male rats received intraperitoneal injections of PbO nanoparticle suspension (2.

Dose-Dependent Effects of Subchronic Lead Exposure on the Right Atrium and Right Ventricle of Rats: An In Vitro Investigation.

Lead poisoning remains a significant threat to both human and animal health, with cardiovascular dysfunction being one of its primary adverse effects. This study aimed to investigate the function of the right atrium and right ventricle in 12-month-old male rats exposed to 5.5, 11, and 22.

On the Mechanisms of the Cardiotoxic Effect of Lead Oxide Nanoparticles.

Lead compounds are one of the most common pollutants of the workplace air and the environment. In the occupational setting, the sources of their emission, including in nanoscale form, are various technological processes associated with lead smelting and handling of non-ferrous metals and their alloys, the production of copper and batteries. Both lead poisoning and lead exposure without obvious signs of poisoning have a detrimental effect on the cardiovascular system.