Navigating Infective Native Aortic Aneurysms in Tropical Regions: Insights from a Five-Year Malaysian Experience.

Background: To describe the clinical characteristics, microbiological profiles, anatomic distribution, operative strategies, and outcomes of patients with infective native aortic aneurysms (INAAs) managed at a high-volume vascular center in Southeast Asia.

Methods: We conducted a retrospective cohort study of 70 patients with INAAs treated surgically or endovascularly between January 2018 and December 2023. Demographics, clinical presentation, microbiological findings, operative data, antibiotic regimens, and follow-up outcomes were analyzed.

A Rare Case of HLA-B51 Positive MAGIC Syndrome: A Clinical Conundrum.

The term mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome was initially dubbed by Firestein et al. in 1985. He described five patients with clinical manifestations of Behcet's disease (BD) as well as relapsing polychondritis (RP), putting forward the terminology MAGIC syndrome to describe the overlap of the two diseases.

An uncommon presentation of segmental Becker's nevus involving the T4 dermatome.

This case report explores a rare manifestation of Becker's nevus, where the patient exhibited an unusual dermatomal distribution featuring a hyperpigmented, irregular patch with associated hypertrichosis on the T4 segment. While Becker's nevus is a well-known dermatological condition typically observed in the upper back region, instances of dermatomal distribution are exceptionally uncommon. This case presents a unique occurrence of segmental Becker's nevus, highlighting the atypical presentation of this condition.

Plausible role of INPP4A dysregulation in idiopathic pulmonary fibrosis.

INPP4A has been shown to be involved in the regulation of cell proliferation and apoptosis of multiple cell types including fibroblasts. Previous reports from our group have demonstrated the role of inositol polyphosphate 4-phosphatase Type I A (INPP4A) in these functions. Though existing evidences suggest a critical role for INPP4A in the maintenance of lung homeostasis, its role in chronic lung diseases is relatively under explored.