Application of Bacterial Cellulose Film as a Wound Dressing in Varicose Vein Surgery: A Randomized Clinical Trial.

Background: Chronic venous insufficiency is common all over the world. It is often related to lower limb varicose veins. Surgical treatment is necessary in most cases but the management of the operative wounds (OW) remains a challenge.

Using risk prediction models to inform personalized, cost-effective treatment recommendations.

Objective: For many medical conditions, rapid, reliable, and affordable diagnostic tests are not available, which leads clinicians to base treatment decisions on patient symptoms and history. Although prediction models can estimate disease risk, they typically do not account for the downstream health or cost consequences of acting on their predictions. We developed and evaluated methods that integrate risk prediction with decision modeling to inform personalized, cost-effective treatment recommendations.

Efficacy and Durability of the Association of Botox and Skinvive in the Treatment of Moderate/Severe Wrinkles in the Periorbital Region: A Randomized, Controlled, Double-Blind, Split-Face Clinical Study.

Background: The combined efficacy and durability of botulinum toxin A (BTX) and hyaluronic acid fillers (HA) for canthal wrinkles have not been thoroughly evaluated in randomized clinical trials.

Aims: This study evaluated the efficacy, safety, and durability of the combined treatment protocol of onabotulinumtoxinA and Juvederm Volite VYC-12 (Skinvive) for moderate and severe canthal lines.

Methods: This randomized double-blinded split-face trial included 25 women with periorbital dynamic wrinkles at severity levels II-IV according to the Merz 5-point scale.

Microwave-Assisted Digestion Method and Dispersive Magnetic Solid-Phase Microextraction for the Determination of Major and Trace Elements in Lignocellulosic Biomass by ICP-OES.

This paper proposes a sample preparation method for the determination of major (Ca, Cu, Fe, Mn, Mg, Na, and Zn) and trace elements (As, Pb, and Se) in lignocellulosic biomass by inductively coupled plasma optical emission spectrometry (ICP-OES). Major composition was determined directly after microwave-assisted digestion with dilute nitric acid, while trace elements were determined using dispersive magnetic solid-phase microextraction (DMSPE). For DMSPE, maghemite nanoparticles were synthesized using the alkaline hydrolysis coprecipitation method and characterized by high-performance scanning microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and thermogravimetric analysis.