Femoral venous stasis index predicts elevated right atrial pressure and mortality in pulmonary hypertension.

Background: Elevated right atrial pressure (RAP) is associated with poor prognosis regarding 1-year mortality in pulmonary hypertension (PH) patients. Unfortunately, there is currently no reliable non-invasive technique for estimating RAP in PH patients. Recently, femoral venous stasis index (FVSI) has been described as highly correlated with RAP in PH patients.

Key motor and non-motor features in early dementia with Lewy bodies.

Objective: The objective of our study was to characterize early-stage dementia with Lewy bodies (DLB) focusing on motor and non-motor symptoms.

Methods: This cross-sectional study prospectively included newly diagnosed DLB patients within 3 years of cognitive symptom onset. Comparisons were made with individuals with Parkinson's disease (PD), Alzheimer's disease (AD), and controls.

Focused Ultrasound as Rescue Treatment of Essential Tremor After Deep Brain Stimulation: 2 Case Reports.

Background And Importance: Approximately 25% to 55% of patients with essential tremor will eventually develop medication-refractory tremor. Currently, the standard surgical treatment for this condition is deep brain stimulation (DBS) of the ventralis intermedius nucleus of the thalamus and, more recently, the posterior subthalamic area. However, MRI-guided focused ultrasound (FUS) thalamotomy has shown promising results in improving tremor in patients with refractory essential tremor.

Perfluoroalkyl substances (PFASs) in groundwater and surface water in the Turin metropolitan area (Italy): An attempt to unravel potential point sources and compliance with environmental/drinking water quality standards.

The study investigated the contribution of five potential point source categories on the occurrence of 19 highly hazardous perfluoroalkyl substances (PFASs) in freshwater from the Turin metropolitan area (Italy) and assessed the quality of groundwater and surface water in compliance with European and Italian guidelines. PFASs were revealed in 29 and 24 % of the investigated shallow (unconfined aquifers) and deep (semi- and confined aquifers) wells with a total concentration, as a sum (ΣPFASs), of 0.01-0.