Prevalence of the Main Human Genetic Variants Related to Resistance to Malaria in a Population of the Colombian Pacific Coast.

Objective: This study aimed to determine the prevalence of Duffy, HbS, HbC, G6PD, and β-thalassemia variants through molecular characterisation in a representative sample of the population from the urban area of Buenaventura, Colombia.

Material And Methods: A total of 819 individuals were randomly selected from 12 communities within the city. Molecular analysis was performed using PCR-RFLP and allele-specific PCR.

Development and modeling of Silk Sericin Gentamicin microparticles as a drug delivery system.

Systemic administration of antibiotics is commonly used to treat infections during wound healing; however, its extensive use has contributed to the emergence of antibiotic-resistant bacteria. The local and controlled delivery of antibiotics is an alternative method for mitigating systemic exposure. This study focused on developing and modeling sericin-gentamicin microparticles as drug delivery systems using a spray-drying process.

Punctate Inner Pachychoroidopathy Associated with Choroidal Neovascularization. A Case Report.

Aims:  To report a case of punctate inner choroidopathy (PIC) with pachychoroid disease features and active choroidal neovascular membrane.

Materials And Methods:  Case report Results: A 33-year-old female patient with a history of myopic neovascular membrane in the right eye (OD), who had received multiple doses of intravitreal Aflibercept, consulted our retina service. Best-corrected visual acuity was 20/40 in OD.

An Updated Review of Infections in Poultry.

Since the early 2000s, skeletal effects, specifically enterococcal spondylitis, related to pathogenic (EC), have been observed in older broiler chicken flocks. This skeletal involvement has typically been associated with persistent EC infections in the free thoracic vertebrae leading to paralysis. However, the emergence of virulent EC in young broiler chicken flocks causing clinical septicemia requires further investigation.

Mitochondrial Retinopathy Due to MT-TL1 Mutation: The Role of Heteroplasmy. A Case Report.

Objective: To report a case of mitochondrial retinopathy, highlighting its clinical and imaging findings, the importance of genetic confirmation, and the possible implications of heteroplasmy in this disease.

Material And Methods: Case report of a mitochondrial retinopathy secondary to m.3243A>G mutation in the MT-TL1 gene.