Hemophagocytic syndrome secondary to canine visceral leishmaniasis: Relationship with clinical score, parasite load and serum cytokines.

Visceral leishmaniasis (VL) is a vector-borne disease which is among the six most important endemic diseases in the world. In Brazil, one of the countries with the highest number of cases, it is caused by the protozoan Leishmania infantum. In humans, VL may be associated with a rare and high-mortality syndrome known as Hemophagocytic Lymphohistiocytosis Syndrome (HLH).

Headaches in juvenile systemic lupus erythematosus patients: a cross-sectional study.

Juvenile systemic lupus erythematosus (jSLE) often involves the central nervous system, with headache being the most common symptom.To describe the frequency, characteristics, and impact on quality of life of headaches in jSLE patients.We conducted a cross-sectional study with jSLE patients under the age of 19 years through chart reviews and questionnaires.

A practical evaluation of AutoML tools for binary, multiclass, and multilabel classification.

Selecting the most suitable Automated Machine Learning (AutoML) tool is pivotal for achieving optimal performance in diverse classification tasks, including binary, multiclass, and multilabel scenarios. The wide range of frameworks with distinct features and capabilities complicates this decision, necessitating a systematic evaluation. This study benchmarks sixteen AutoML tools, including AutoGluon, AutoSklearn, TPOT, PyCaret, and Lightwood, across all three classification types using 21 real-world datasets.

Target Isolation of Prenylated Isoflavonoids and Pterocarpans from Using LC-MS/MS-Based Molecular Networking.

This is the report of the HPLC-MSn-guided isolation of new anti-inflammatory prenylated isoflavonoids and pterocarpans from the stems of using GNPS molecular networking as the main tool. Cluster analysis guided the isolation of five new prenylated isoflavonoids, diffusiflavone A-E ( and ), two prenylated pterocarpans, diffusicarpan A and B ( and ), and two known compounds 6-prenylorobol () and 3--methylquercetin (). The in vitro anti-inflammatory potential of compounds and was assessed in macrophages induced with lipopolysaccharide (LPS).

Fungal and bacterial diversity present on the rind and core of Natural Bloomy Rind Artisanal Minas Cheese from the Canastra region, Brazil.

Globally recognized for its unique sensory attributes, Natural Bloomy Rind Artisanal Minas Cheese (NBRAMC) from the Canastra microregion is made from raw cow's milk using a natural starter culture derived from the local environment. During ripening process, microorganisms, predominantly Geotrichum candidum, develop on the surface, with the microbial community playing a crucial role in shaping the cheese's distinctive characteristics. This study aimed to characterize the microbial community, including filamentous fungi, yeasts, and bacteria, present in the rind and core of NBRAMC.