Vasomotion in Human Fingers.

Introduction: We describe methods by which vasomotion can be recorded in awake and anesthetized human subjects without significant interference from other spontaneous vascular oscillations.

Methods: In three separate studies we used photoplethysmography to record vasomotion in fingertips. In Study 1 we induced chemical sympathectomy in the studied hand of 11 awake subjects who received intravenous dexmedetomidine infusions.

Levator Muscle Complex Exploration During Surgery for Simple Severe Congenital Ptosis.

Purpose: To describe the gross morphology of the levator palpebrae superioris (LPS) muscle complex in severe congenital ptosis with poor levator function (LF) and to evaluate the surgical outcomes when levator surgery was performed based on intraoperative factors.

Methods: This is a retrospective, interventional case series that includes children having simple severe congenital ptosis with LF ≤ 4 mm for whom levator muscle surgery was performed rather than preplanned frontalis suspension based on the intraoperative LPS muscle evaluation. The collected data included: demographics; ptosis measurements, including margin reflex distance 1 and LF; morphological appearance of LPS muscle and its aponeurosis (levator aponeurosis); surgical technique, and outcomes.

Prevalence and molecular characterization of multidrug resistant Campylobacter isolated from animals and humans as a one health approach.

Campylobacteriosis is a significant zoonosis with major public health implications. This study aimed to investigate the prevalence, molecular characteristics, and antimicrobial resistance of Campylobacter spp. in animal (rectal swabs and milk), environmental (fecal, water, and wall swabs), and human samples (stool and hand swabs) in New Valley Governorate, Egypt.

A comprehensive review on computational metabolomics: Advancing multiscale analysis through approaches.

Computational metabolomics will be established in drug discovery and research on complex biological networks. This field of research enhances the detection of metabolic biomarkers and the prediction of molecular interactions by combining multiscale analysis with and molecular docking methods. These include nuclear magnetic resonance, mass spectrometry, and innovative bioinformatics, which enable the accurate generation and characterization of metabolomes.

Early extraction versus conservative management in patients with noninfected cardiac implantable electronic devices undergoing cardiac surgery for left-sided infective endocarditis: Insights from the multicentric Clinical Multicenter Project for Analysis of Infective Endocarditis in Germany Registry.

Objectives: This study aimed to analyze the outcomes of patients with left-sided infective endocarditis (IE) and noninfected cardiac implantable electronic device (CIED) undergoing cardiac surgery, with a focus on whether the CIED was removed.

Methods: Retrospective analysis based on the Clinical Multicenter Project for Analysis of Infective Endocarditis in Germany Registry, comprising patients with left-sided IE who underwent valve surgery between 1994 and 2018 in 6 German centers. Two treatment strategies were compared: CIED extraction versus no extraction.