Pelvic radiotherapy is an acceptable and promising treatment modality for various pelvic malignancies. However, it is associated with radiation-induced injury on surrounding structures with a preference for the rectum, which is characteristically fixed in the pelvic region. Acute radiation proctitis is usually self-limiting, but in its chronic form, it can be debilitating.
View Article and Find Full Text PDFVirulence
December 2023
Hepatitis B virus (HBV) immune escape and Pol/RT mutations account for HBV immunoprophylactic, therapeutic, and diagnostic failure globally. Little is known about circulating HBV immune escape and Pol/RT mutants in Nigeria. This study focused on narrowing the knowledge gap of the pattern and prevalence of the HBV mutants across clinical cohorts of infected patients in southwestern Nigeria.
View Article and Find Full Text PDFHepatitis B virus (HBV) infection follows a natural course of events predicted by a dynamic interaction between viral antigen and the host immune system, which forms the basis for HBV serological diagnosis. These interactions may deviate from the typical serologic patterns. This study investigates the types of atypical HBV serologic profiles (AHBSP) across clinical cohorts of patients with HBV infection in southwestern Nigeria.
View Article and Find Full Text PDFIntroduction: Hepatitis D virus (HDV) is a satellite virus of hepatitis B virus (HBV). An estimated 5% of HBV infected individuals worldwide have HDV infection. There is paucity of studies in Nigeria on the burden of HDV infection.
View Article and Find Full Text PDFIntroduction: Myxoma is the most common primary cardiac tumour. This case report illustrates the case of a probable right atrial myxoma prolapsing through the tricuspid valve into the right ventricle, and the fatal outcome if such a mass is not promptly detected and excised.
Case Presentation: A 51-year old man presented with a 1-year history of recurrent pedal and abdominal swelling, and 6-month history of progressive dyspnoea on exertion.