The Impact of Sarcopenia on Clinical Outcomes in Pediatric Crohn's Disease.

Background: The effect of sarcopenia on clinical outcomes in children with Crohn's disease (CD) is unknown. We investigated whether sarcopenia at the diagnosis impacts the outcomes of children with CD.

Methods: This was a retrospective, single-center, case-control study of newly diagnosed children with CD undergoing magnetic resonance (MR) within 1 month from the diagnosis, from 2011 to 2022.

Is transmural healing better than mucosal healing in pediatric Crohn's disease?

Background: Limited data exist on the long-term benefits of transmural healing (TH) in pediatric Crohn's disease (CD).

Aims: To evaluate outcomes children with CD achieving TH compared to those with mucosal healing (MH) and no healing (NH).

Methods: Retrospective, single-center study including children with CD undergoing magnetic resonance enterography (MRE), ileocolonoscopy, and/or capsule endoscopy within a three-month interval.

Magnetic Resonance Imaging of the Gastrointestinal Tract: Current Role, Recent Advancements and Future Prospectives.

This review focuses on the role of magnetic resonance imaging (MRI) in the evaluation of the gastrointestinal tract (GI MRI), analyzing the major technical advances achieved in this field, such as diffusion-weighted imaging, molecular imaging, motility studies, and artificial intelligence. Today, MRI performed with the more advanced imaging techniques allows accurate assessment of many bowel diseases, particularly inflammatory bowel disease and rectal cancer; in most of these diseases, MRI is invaluable for diagnosis, staging, and disease monitoring under treatment. Several MRI parameters are currently considered activity biomarkers for inflammation and neoplastic disease.

Multi-parametric MRI in the diagnosis and scoring of gastrointestinal acute graft-versus-host disease.

Objectives: Acute gastrointestinal graft-versus-host disease (GI-aGVHD) is a severe complication of allogeneic hematopoietic stem cell transplantation (HSCT). Diagnosis relies on clinical, endoscopic, and pathological investigations. Our purpose is to assess the value of magnetic resonance imaging (MRI) in the diagnosis, staging, and prediction of GI-aGVHD-related mortality.