Publications by authors named "Lorena Charrier"

Online surveys often suffer from low response rates, raising concerns about the representativeness and validity of resulting estimates. We evaluated the impact of calibration weighting on data from a cross-sectional online survey on mental health and well-being conducted among university students at the University of Torino, Italy, which had a ~ 10% response rate (eligible population ~ 79,000). Calibration was performed on data from 5,284 students using the raking method and auxiliary variables (sex, course area, and course cycle) to improve representativeness.

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Adoptees, a group of children consistently shown to be at higher risk of psychosocial difficulties, face particular challenges during adolescence. However, few studies address the well-being of adopted adolescents, and cross-cultural comparisons are rarely reported. The present study assessed the life satisfaction of internationally adopted and non-adopted adolescents living in four European countries.

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Purpose: Patient perceptions of care quality can guide targeted improvements. Valid and reliable measures are essential for meaningful patient satisfaction assessment, but no validated questionnaires were found among those used in most Italian hospitals. This study aimed to assess the internal reliability and construct validity of two patient satisfaction questionnaires (one for outpatient care and one for inpatient care) developed at Ordine Mauriziano Hospital in Torino, Italy.

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Aims: To investigate adolescents' perception of the impact of the COVID-19 pandemic on several aspects of their lives (mental health, well-being, family situation, peers, school, dieting, and physical activity) in relation to risk behaviors such as smoking, alcohol use, drunkenness, and cannabis use.

Methods: Data were used from the Health Behaviour in School-aged Children (HBSC) study conducted in 2021/2022, comprising 106,221 adolescents aged 11-15 (50.9% females) from 21 European countries.

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Article Synopsis
  • Streptococcus pneumoniae
  • in Piedmont, Italy.
  • * Data from 2008 to present showed that out of 2,076 strains collected, 21.9% were resistant to penicillin G and 40.3% to erythromycin, with an overall increased risk of penicillin-resistant infections across all age groups.
  • * The findings indicate a significant rise in penicillin G-resistant pneumococcal disease particularly among infants and the elderly following vaccination implementation, while the SARS-CoV2 pandemic didn't show a significant impact on AMR
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  • A study investigates the link between apical periodontitis (AP) and elevated serum inflammatory factors that might trigger insulin resistance (IR), aiming to understand the potential impact of root canal treatment (RCT) on inflammation and insulin response.
  • Results showed untreated AP patients had significantly higher levels of proinflammatory cytokines (IL-1, IL-6, IL-8) compared to healthy controls, suggesting a connection between AP and systemic inflammation.
  • Post-treatment, patients with AP displayed reduced cytokine levels and an improved insulin response, indicating that RCT may alleviate inflammation and its effects on insulin sensitivity.
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  • Twin pregnancies have a higher risk of preterm birth and related health issues, partly due to infections like lower genital tract infections (LGTIs) and bacterial vaginosis which are linked to preterm labor in singleton pregnancies but need more research for twins.* -
  • This study compared two groups of women with twin pregnancies: one group was tested for infections only once at 20-22 weeks (Single Test Group), while the other group was tested twice at 12-14 weeks and again at 20-22 weeks (Double Test Group). Both groups were monitored at Sant'Anna Hospital in Italy from 2012 to 2021.* -
  • The results indicated that early screening and treatment in the Double Test
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Background: Health care workers (HCWs) are at increased risk of exposure to hepatitis B virus (HBV). The most effective prevention measure is vaccination, with a serum hepatitis B surface antibody (HBsAb) titre > 10 mIU/ml considered protective. To date, the sociodemographic and occupational characteristics related to HBV serosusceptibility and factors associated with booster hesitancy remain unclear.

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Despite its decrease in many Western countries, cannabis remains the most used illicit substance among adolescents. This study aims to summarize cannabis consumption during the last two decades and project trends among 15-year-olds in the 2021-22 HBSC survey. A Bayesian semi-parametric hierarchical model was adopted to estimate the trend of cannabis consumption using data of about 287,000 adolescents from the 2001/2002 to the 2017/2018 HBSC wave and the 38 countries that met the inclusion criteria.

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Objective: Noninvasive mechanical ventilation (NIMV) improves amyotrophic lateral sclerosis (ALS) quality of life and survival. However, data about its effect on disease progression are still lacking. Here, we test whether NIMV use changed the rate of functional decline among ALS patients.

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Adolescence is a critical period for engaging in health risk behaviors. Migrant adolescents may face unique challenges due to acculturation stress. This study aims to monitor substance use and problem gambling among migrant adolescents living in Italy.

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The study aims to evaluate the health profile of first- and second-generation Romanian immigrants living in Italy compared to their adolescent peers in the country of origin (Romania) and the host population (Italian-borns). Analyses were performed on the 2013/2014 Health Behaviour in School-aged Children (HBSC) survey data. Romanian natives showed lower levels of health complaints and higher life satisfaction than Romanian migrants, who were similar to the host population, especially the second-generation ones.

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This study was aimed at investigating risk factors for mortality in patients suffering from KPC-producing Klebsiella pneumoniae (KPC-Kp) bloodstream infections (BSIs), evaluating the impact of rapid diagnostics and ceftazidime/avibactam use. This observational retrospective study (January 2017-May 2021) included all patients with a KPC-Kp BSI. Uni-multivariable analyses were carried out to evaluate the effect of clinical variables on both in-hospital death (IHD) and 30-day all-cause mortality, and the role of the combination of ceftazidime/avibactam plus polymyxin.

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(1) Background: In Italy, the components of adolescents' mental well-being (psychological symptomatology and cognitive perception of life satisfaction) showed different temporal trends, suggesting the adoption of a multidimensional conceptualization. We aimed to assess temporal patterns and provide additional insights into Italian adolescents' mental well-being in the last decade by adopting the Dual Factor Model; (2) Methods: We used nationally representative samples of Italian students (n = 165,000) aged 11, 13, and 15 years across the three more recent Italian Health Behaviour in School-aged Children (HBSC) surveys. Two measures of mental well-being were used: life satisfaction (LS, indicator of positive subjective well-being) and psychological health complaints (PHC, indicator of mental illness); (3) Results: Our study showed that the overall sample has been moving from a Complete Mental Health (Flourishing) to an Incomplete Mental Illness (Struggling) condition.

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Objectives: This study aimed at exploring 2020/2021 and 2019/2020 seasonal influenza vaccine uptake among healthcare and non-healthcare workers, hereafter hospital-based workers (HBWs); examining attitudes and motivations for uptake in the 2020/2021 season; and exploring the amount, types, and sources of information used by HBWs.

Methods: A retrospective cohort study. Socio-demographics, working profile, working area, and vaccination status data were collected.

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The debate on vaccination mandate was fuelled over the past two years by the COVID-19 pandemic. This study aimed at overviewing vaccination strategies and corresponding vaccine coverages for childhood vaccinations before the pandemic and for SARS-CoV-2 in high-income countries. A qualitative comparison was also performed between the two contexts: unlike for childhood vaccinations, only one European country (Austria) imposed generalised COVID-19 mandates, most countries preferring targeted mandates for higher-risk categories (Italy, Greece) or workers in key public services (Finland, Australia, New Zealand, UK, Germany).

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Higher family affluence is associated with healthier behaviours in adolescents, but the strength of this association varies across countries. Differences in social mobility at the country-level, i.e.

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Recent studies have examined how the environment can influence obesity in young people. The research findings are conflicting: in some studies, green spaces have shown a protective association with obesity and urbanization has turned out to worsen this condition, while other studies contradicted these results. The aim of the study was to examine the relationships between greenness, urbanization, and weight status among Italian adolescents.

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Introduction: The Italian "Health Behaviour in School-aged Children" (HBSC) is a national surveillance system that collects data on health and well-being among adolescents aged 11, 13 and 15 years attending school. It is part of the HBSC Research Network, an international alliance of researchers from 45 European and North American countries and regions started in 1982.

Methods: All countries and regions participating in HBSC must adhere to a common international standard protocol developed and systematically updated by the entire HBSC Network.

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The aim of this study was to describe physical activity, both moderate-to-vigorous physical activity (MVPA) and vigorous physical activity (VPA), in a large nationally representative sample of Italian adolescents, aged 11, 13 and 15, and to evaluate if Italian adolescents were in line with the 2020 WHO recommendations. In order to assess the possible impact of physical activity on adolescent psychological and social wellbeing, the associations between MVPA and VPA with life satisfaction, self-rated health and peer relationships were also explored. Data from the 2018 Italian Health Behaviour in School-aged Children (HBSC) survey on 58,976 adolescents were analysed.

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(1) Aim: To summarize alcohol trends in the last 30 years (1985/6-2017/8) among 15-year-olds in Health Behaviour in School-aged Children (HBSC) countries (overall sample size: 413,399 adolescents; 51.55% girls) and to forecast the potential evolution in the upcoming 2021/22 HBSC survey. (2) Methods: Using 1986-2018 prevalence data on weekly alcohol consumption among 15-year-olds related to 40 HBSC countries/regions, a Bayesian semi-parametric hierarchical model was adopted to estimate trends making a clusterization of the countries, and to give estimates for the 2022 HBSC survey.

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Background: Although the relationship between problematic social media use (PSMU) and happiness has been already explored, less is known about the mechanisms that translate PSMU into lower happiness through lifestyle habits. Therefore, the current study focuses on the association between PSMU and happiness, exploring a mediating effect of lifestyle habits (e.g.

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(1) Aims: To explore temporal trends 2010-2018 of well-being among Italian adolescents and to evaluate potential explanatory factors. (2) Methods: Italian nationality representative samples of students aged 11, 13, and 15 years were recruited in 2010, 2014, and 2018; Health Behaviour in School-aged Children (HBSC), for an overall number of 165,000 teenagers. Multivariable logistic regression models were performed to fit the trends over time of life satisfaction (LS), psychological (PSY-HC) and somatic health complaints (SOM-HC) considering the contextual factors: school work pressure, social support (family, school, peers), socioeconomic status, geographic area, and immigration background; (3) Results: From 2010 to 2018 while LS was steady, health complaints increased, mainly for PSY-HC, in all age and gender groups.

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