Publications by authors named "Lisa M D Grymyr"
Background: The long-term impact of bariatric surgery on cardiac mechanics and energetics has been scarcely documented. We aimed to assess prospectively the 5-year trajectories of left heart geometry, mechanics, and myocardial oxygen (O) demand after bariatric surgery.
Methods: In the Bariatric Surgery on the West Coast of Norway study, left ventricular (LV) and atrial remodeling was evaluated preoperatively, 6 months, and 1 and 5 years after Roux-en-Y gastric bypass in 102 patients.
Background: Incidence of cryptogenic ischemic stroke (CIS) in young adults is increasing. Early left atrial (LA) myopathy might be 1 of the underlying mechanisms, but this has only been scarcely explored.
Objectives: The purpose of this study was to assess the association between increased LA stiffness and CIS in young adults.
Aims: Mitral regurgitation (MR) causes left atrial (LA) enlargement and impaired reservoir function. We assessed whether changes in LA size, strain, and stiffness in significant (moderate or greater) primary MR are sex-specific.
Methods And Results: In the 3D Echocardiography and Cardiovascular Prognosis in Mitral Regurgitation study, 111 patients with primary MR were prospectively investigated with 2D and 3D echocardiography.
Article Synopsis
- * A study involving 75 patients showed that while bariatric surgery improved body mass index (BMI) and some measures of heart function, over one-third still had issues with midwall shortening (MWS) a year later.
- * Preoperative evaluations using a risk index based on factors like sex, hypertension, ejection fraction, and levels of inflammatory proteins can effectively identify patients at high risk for impaired heart mechanics after surgery.
Aims: Patients with severe obesity are predisposed to left ventricular (LV) hypertrophy, increased myocardial oxygen demand, and impaired myocardial mechanics. Bariatric surgery leads to rapid weight loss and improves cardiovascular risk profile. The present prospective study assesses whether LV wall mechanics improve 1 year after bariatric surgery.
View Article and Find Full Text PDFBackground: Aortic valve sclerosis (AVS), mitral valve sclerosis (MVS), remodeling of major arteries, and increased pericardial fat are associated with subclinical atherosclerosis. We assessed these markers of atherosclerosis in severely obese patients before and 1 year after bariatric surgery. Methods: Eighty-seven severely obese patients (43 ± 10 years, preoperative body mass index [BMI] 41.
View Article and Find Full Text PDFLeft ventricular myocardial oxygen demand and subclinical dysfunction in patients with severe obesity referred for bariatric surgery.
Nutr Metab Cardiovasc Dis
February 2021
Background And Aims: Increased myocardial oxygen (O) demand carries higher cardiovascular risk in hypertension. We hypothesized that myocardial O demand is increased in severe obesity and linked to early left ventricular (LV) dysfunction.
Methods And Results: Baseline data from 106 severely obese subjects referred for gastric bypass surgery (42 ± 11 years, 74% women, body mass index [BMI] 41.