Publications by authors named "Linmin Zhong"

Environmental arsenic exposure and Helicobacter pylori (H. pylori) infection are widespread public health concerns, yet their combined effects on gastric pathophysiology remain poorly understood. This study investigated the impact of H.

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Article Synopsis
  • Environmental arsenic contamination often exceeds safety levels in drinking water and is linked to higher rates of H. pylori infections, leading to concerns about the combined effects of both hazards.
  • A study using a mouse model found that exposure to both H. pylori and inorganic arsenic resulted in significant changes in intestinal flora composition and metabolic processes.
  • The research suggests that H. pylori may worsen the imbalance in gut bacteria and disrupt liver metabolism caused by arsenic, which could heighten sensitivity to heavy metal toxicity.
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Single nucleotide polymorphisms (SNPs) present significant challenges in microbial detection and treatment, further raising the demands on sequencing technologies. In response to these challenges, we have developed a novel barcode-based approach for highly sensitive single nucleotide recognition. This method leverages a dual-head folded complementary template probe in conjunction with DNA ligase to specifically identify the target base.

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