Publications by authors named "Libby Hanwell"
Article Synopsis
- Dimethylsulfoniopropionate (DMSP) is a vital marine compound involved in stress protection, nutrient cycling, and regulating the climate.
- The enzyme DsyGD, found in certain bacteria and previously unrecognized cyanobacteria, plays a key role in DMSP biosynthesis via two distinct functional domains.
- New findings reveal that algae with a variant protein called DSYE are significant DMSP producers, particularly highlighting the role of Pelagophyceae species in global sulfur cycling.
RirA is a global iron regulator in diverse that belongs to the Rrf2 superfamily of transcriptional regulators, which can contain an iron-sulfur (Fe-S) cluster. Under iron-replete conditions, RirA contains a [4Fe-4S] cluster, enabling high-affinity binding to RirA-regulated operator sequences, thereby causing the repression of cellular iron uptake. Under iron deficiency, one of the cluster irons dissociates, generating an unstable [3Fe-4S] form that subsequently degrades to a [2Fe-2S] form and then to apo RirA, resulting in loss of high-affinity DNA-binding.
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