Publications by authors named "Leping Peng"
Objectives: Preoperative prediction of lymph node metastasis (LNM) is important for gastric cancer (GC) diagnosis, treatment and prognosis. This study aimed to predict LNM risk in GC using quantitative parameters and extracellular volume fraction (ECV%) derived from spectral computed tomography (CT).
Materials And Methods: Data from 230 lymph nodes (LNs) (97 nonmetastatic, 133 metastatic) were collected from 70 GC patients and were randomly divided into a training cohort and a test cohort (6:4 ratio).
Objectives: To develop a nomogram that combines dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) perfusion parameters, ADC values and clinical features to preoperatively identify microsatellite instability (MSI) in patients with colorectal cancer (CRC).
Methods: This retrospective study included 63 CRC patients who underwent preoperative DCE-MRI and had immunohistochemistry results available. Two radiologists, in a double-blind manner, placed two circular regions of interests in the area with the highest perfusion intensity on the DCE-MRI perfusion map and the corresponding area on the ADC map.
Rationale And Objectives: Microsatellite instability (MSI) stratification can guide the clinical management of patients with colorectal cancer (CRC). This study aimed to establish a radiomics model for predicting the MSI status of patients with CRC before treatment.
Materials And Methods: This retrospective study was performed on 366 patients diagnosed with CRC who underwent preoperative magnetic resonance imaging (MRI) and immunohistochemical staining between February 2016 and September 2023.