Publications by authors named "Lepeng Zhou"

Background: Cesarean section is considered as a potential risk factor for early childhood (0-6 years) overweight/obesity; however, the precise magnitude of this risk remains unclear.

Objectives: To estimate the risk of early childhood overweight/obesity in children delivered by cesarean section through a systematic review.

Search Strategy: MEDLINE, Embase, Web of Science, CNKI and Wanfang databases were searched using a combination of relevant terms for cesarean section, overweight/obesity and children.

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MXenes hold great promise for flexible sensors due to their outstanding electrical and mechanical properties. However, their practical application in aqueous environments is often compromised by oxidation susceptibility. Here, epigallocatechin gallate (EGCG), a naturally derived compound is introduced, as a protective coating for Ti₃C₂T MXene nanosheets.

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Objective: To comprehensively summarize the existing evidence on the effectiveness of vaginal microbiota transplantation (VMT) in treating vaginal dysbiosis (VD) and bacterial vaginosis (BV).

Methods: Following the PRISMA-ScR guidelines, a scoping review was conducted through October 10, 2023, using the databases PubMed, Embase, Scopus, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang, SinoMed, Weipu (VIP), ClinicalTrials.gov and the Chinese clinical trial registry.

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Introduction: Understanding the mechanisms underlying maternal postpartum depression (PPD) and its effects on offspring development is crucial. However, research on the association between maternal PPD, gut microbiota, and offspring neurodevelopment remains limited. This study aimed to examine the association of maternal PPD symptoms with early gut microbiome, gut metabolome, and neurodevelopment in infants at 6 months.

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C-section is crucial in reducing maternal and neonatal mortality when medically indicated, but one of its side effects could be the disruption of vertical transmission of maternal-infant microbiota during delivery, potentially leading to gut dysbiosis and increased disease risks in C-section infants. To address such dysbiosis, it seems reasonable to supplement "what is missing" during C-section procedure. This idea has prompted several clinical trials, including proof-of-concept, investigating interventions like vaginal microbial seeding, oral administration of maternal vaginal microbes and even oral administration of maternal fecal materials.

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The microbiomes of cesarean-born infants differ from vaginally delivered infants and are associated with increased disease risks. Vaginal microbiota transfer (VMT) to newborns may reverse C-section-related microbiome disturbances. Here, we evaluated the effect of VMT by exposing newborns to maternal vaginal fluids and assessing neurodevelopment, as well as the fecal microbiota and metabolome.

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Background: Although birth trauma may be a risk factor for postpartum post-traumatic stress disorder (PTSD), no systematic review regarding the incidence of postpartum PTSD in women with traumatic childbirth has been reported.

Objective: To estimate the incidence of PTSD in women following traumatic childbirth by systematically reviewing and synthesizing all available evidence.

Search Strategy: Six databases were searched using a combination of related terms for birth trauma and PTSD.

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Background: Research on the association between breastfeeding and postpartum post-traumatic stress disorder (PTSD) is sparse. This study aimed to examine the association between exclusive breastfeeding up to 42 days after childbirth and postpartum PTSD.

Methods: An epidemiologic study was conducted in a tertiary hospital in China between October 2019 and October 2020.

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Article Synopsis
  • - The study investigates the prevalence of eczema in infants under one year old, comparing those born via cesarean section to those born vaginally, using a systematic review and meta-analysis of nine studies.
  • - Results show that 27.8% of cesarean-born infants have eczema, which is significantly higher than the 20.1% found in vaginal-born infants, yielding a pooled odds ratio of 1.31.
  • - Factors like study design, country, and method of eczema identification were found to affect the variations in prevalence, indicating that cesarean birth may be linked to higher eczema rates.
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Grade 4 peripheral intravenous infiltration with skin tears has seldom been reported. On 4 August 2020, a 35-year-old female patient was admitted to the emergency department of our hospital because of postprandial abdominal pain for 2 hours. She was diagnosed with a severe acute pancreatitis with type II diabetes mellitus.

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Objective: Comprehensive comparison of maternal and neonatal outcomes between placenta previa with and without a history of caesarean delivery is sparse in the literature. The objective of this study was to conduct such an analysis.

Methods: We conducted a retrospective cohort study involving all cases of placenta previa among 56 070 singleton births at two tertiary care hospitals in Guangdong, China, between January 2014 and December 2018.

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Coronavirus disease 2019 (COVID-19) has become a pandemic with no specific and widely accepted effective drug or vaccine. However, studies have shown that Traditional Chinese Medicine (TCM) may play a significant role as an auxiliary treatment for COVID-19. This study aimed to assess the effects of TCM as an auxiliary treatment for COVID-19 through a systematic review of randomized-controlled trials (RCTs).

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