Publications by authors named "Leonardo Pasquetti"

This study aimed to assess the impact of active malignancy on outcomes in patients undergoing revascularization for acute limb ischemia (ALI), focusing on mortality, limb salvage, and patency loss. We conducted a retrospective analysis of consecutive patients with ALI who underwent lower-limb revascularization over a 7-year period. Patients were stratified into two groups based on the presence of active malignancy at ALI diagnosis.

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PurposeTo evaluate the safety and efficacy of cadaveric skin and dermal grafts from skin banks in the management of hard-to-heal wounds (HHWs), particularly of vascular etiology, in a frail patient population.MethodsThis prospective, single-center study enrolled 48 patients with HHWs unresponsive to conventional care. Patients underwent vascular assessment, revascularisation if indicated, and wound bed preparation prior to application of cryopreserved, glycerol-preserved, or lyophilized cadaveric grafts.

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Introduction: Chronic limb-threatening ischemia (CLTI) is a severe manifestation of peripheral artery disease, frequently associated with multimorbidity and polypharmacy. Chronic low-grade inflammation plays a pivotal role in atherosclerosis progression, and hematologic markers such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) are gaining value as prognostic tools.

Aim: To investigate the relationship between the Comorbidity-Polypharmacy Score (CPPS) and inflammatory biomarkers in patients undergoing elective revascularization for CLTI.

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The detachment of components of endovascular devices is a rare but potentially harmful complication. This report describes a clinical case of nosecone detachment from an iliac branch device delivery system during an aortoiliac aneurysm exclusion in a 73-year-old male patient. After correct deployment, the iliac branch device nosecone detached during the removal of the delivery system.

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Intraprocedural endovascular device fracture and migration is an uncommon complication, with potential catastrophic outcomes. In a 75-year-old woman, retrograde puncture of the superficial femoral artery led to accidental femoral vein puncture and wire coating fragmentation. The fragment migrated up to a sublobar branch of the left pulmonary artery, and again to the right pulmonary artery during the first retrieval attempt.

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Article Synopsis
  • - The study evaluated the geometrical effects of three different carotid stents on the carotid bifurcation in patients who underwent carotid artery stenting (CAS), revealing variations in anatomical changes after stent placement.
  • - A total of 226 patients were analyzed, showing the Roadsaver stent resulted in a greater change in the angle between common carotid artery (CCA) and internal carotid artery (ICA) compared to the other two stents, but this did not significantly affect the rate of restenosis.
  • - Overall, the Roadsaver stent's lower adaptability to the carotid vascular area suggests it might cause more pronounced angulations post-implantation, while the Carotid Wallstent and C
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