This study aimed to assess the impact of active malignancy on outcomes in patients undergoing revascularization for acute limb ischemia (ALI), focusing on mortality, limb salvage, and patency loss. We conducted a retrospective analysis of consecutive patients with ALI who underwent lower-limb revascularization over a 7-year period. Patients were stratified into two groups based on the presence of active malignancy at ALI diagnosis.
View Article and Find Full Text PDFInt J Low Extrem Wounds
July 2025
PurposeTo evaluate the safety and efficacy of cadaveric skin and dermal grafts from skin banks in the management of hard-to-heal wounds (HHWs), particularly of vascular etiology, in a frail patient population.MethodsThis prospective, single-center study enrolled 48 patients with HHWs unresponsive to conventional care. Patients underwent vascular assessment, revascularisation if indicated, and wound bed preparation prior to application of cryopreserved, glycerol-preserved, or lyophilized cadaveric grafts.
View Article and Find Full Text PDFIntroduction: Chronic limb-threatening ischemia (CLTI) is a severe manifestation of peripheral artery disease, frequently associated with multimorbidity and polypharmacy. Chronic low-grade inflammation plays a pivotal role in atherosclerosis progression, and hematologic markers such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) are gaining value as prognostic tools.
Aim: To investigate the relationship between the Comorbidity-Polypharmacy Score (CPPS) and inflammatory biomarkers in patients undergoing elective revascularization for CLTI.
J Vasc Surg Cases Innov Tech
August 2025
The detachment of components of endovascular devices is a rare but potentially harmful complication. This report describes a clinical case of nosecone detachment from an iliac branch device delivery system during an aortoiliac aneurysm exclusion in a 73-year-old male patient. After correct deployment, the iliac branch device nosecone detached during the removal of the delivery system.
View Article and Find Full Text PDFIntraprocedural endovascular device fracture and migration is an uncommon complication, with potential catastrophic outcomes. In a 75-year-old woman, retrograde puncture of the superficial femoral artery led to accidental femoral vein puncture and wire coating fragmentation. The fragment migrated up to a sublobar branch of the left pulmonary artery, and again to the right pulmonary artery during the first retrieval attempt.
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