Real-world treatment patterns in patients with generalized pustular psoriasis (GPP).

Background: Generalized pustular psoriasis (GPP) is a chronic and life-threatening inflammatory skin disease, distinct from plaque psoriasis (PsO). There is a lack of GPP treatment guidelines.

Objective: To characterize treatment patterns among patients with GPP in the US during two 365-day periods (post-diagnosis and pre-diagnosis) between 2015 and 2020.

Real-world clinical characteristics and treatment patterns of generalized pustular psoriasis flares.

Background: Clinical characteristics and treatment of generalized pustular psoriasis (GPP) flares are poorly understood.

Objective: To characterize patients by GPP flare status, quantify flare timing/frequency, and understand peri-flare treatment patterns.

Methods: This cohort study utilized electronic health records (2017-2023) from outpatient dermatology clinics in the OMNY Health real-world data platform.

Healthcare Resource Utilization Among Patients With Generalized Pustular Psoriasis: The Impact of Flares and Disease Severity.

Background: Generalized pustular psoriasis (GPP) is a rare, chronic, often unpredictable, severe multisystemic autoinflammatory skin disease from which patients can experience flares, episodes of widespread eruptions of painful, sterile pustules often accompanied by systemic symptoms. The impact of GPP flares and underlying GPP severity on the healthcare resource utilization (HCRU) is not well characterized.

Objective: To quantify HCRU among US GPP patients by flare status and underlying severity.

Stillbirths and early neonatal mortality in rural Northern Ghana.

Objective: To calculate perinatal mortality (stillbirth and early neonatal death: END) rates in the Upper East region of Ghana and characterize community-based stillbirths and END in terms of timing, cause of death, and maternal and infant risk factors.

Methods: Birth outcomes were obtained from the Navrongo Health and Demographic Surveillance System over a 7-year period.

Results: Twenty thousand four hundred and ninty seven pregnant women were registered in the study.