Dynamic remodeling of centrioles and the microtubule cytoskeleton in the lifecycle of chytrid fungi.

Cell movement and division are complex behaviors driven by a dynamic internal cytoskeleton. The molecular components and principles of cytoskeletal assembly are well studied, but less is known about cytoskeletal remodeling events, including how centrioles transition from ciliary base to centrosome. Here we address this using the chytrid a zoosporic fungus which has centrioles and cilia, lost in most fungal lineages.

Dynamic remodeling of centrioles and the microtubule cytoskeleton in the lifecycle of chytrid fungi.

Cells reorganize in space and time to move and divide - complex behaviors driven by their internal cytoskeleton. While we have substantial knowledge of the molecular parts and rules of cytoskeletal assembly, we know less about how structures are remodeled, for example to interconvert centrioles from the ciliary base to the centrosome. To study this in an evolutionary context we use the chytrid fungus, , a member of the zoosporic fungi which have centrioles and cilia, lost in other fungal lineages.