Publications by authors named "Konstantinos Theodoropoulos"

Background: Safety and efficacy of intravascular ultrasound (IVUS) guidance in percutaneous coronary intervention (PCI) has been consistently shown in recent trials. However, prospective data on the clinical effects of IVUS usage in primary PCI are still warranted. The ULTRA-STEMI trial is a prospective investigator-initiated observational single-center cohort trial aiming to enroll 80 patients with STEMI.

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Managing dual antiplatelet therapy (DAPT) perioperatively is challenging, especially in patients who have recently undergone percutaneous coronary intervention (PCI). Intravenous antiplatelet agents are recommended in these cases. This case series describes the perioperative management of two high bleeding risk patients with recent PCI undergoing cardiac and non-cardiac surgeries using cangrelor monotherapy.

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The transradial artery has been established as the default access site for most coronary catheterization procedures with fewer access-related and bleeding complications, rapid hemostasis, early ambulation of the patient, and reduction in all-cause mortality compared with transfemoral access. However, radial artery occlusion (RAO) remains the most frequent complication of coronary catheterization procedures performed via transradial artery access. The purpose of our review was to conduct detailed literature research and summarize all the available treatment strategies for RAO, given the lack of a standardized treatment protocol in the literature.

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Psoriasis predisposes to cardiovascular dysfunction. We investigated whether glycocalyx dietary supplement (GDS), which contains glycosaminoglycans and fucoidan, improves endothelial glycocalyx and arterial stiffness in psoriatic patients. Fifty participants with psoriasis under biological agents were randomly assigned to GDS (n = 25) or placebo (n = 25) for 4 months.

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Engaging intracoronary imaging (IC) techniques such as intravascular ultrasound or optical coherence tomography enables the precise description of vessel architecture. These imaging modalities have well-established roles in providing guidance and optimizing percutaneous coronary intervention (PCI) outcomes. Furthermore, IC is increasingly recognized for its diagnostic capabilities, as it has the unique capacity to reveal vessel wall characteristics that may not be apparent through angiography alone.

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Article Synopsis
  • The study examined the incidence of radial artery occlusion (RAO) in patients undergoing transradial coronary catheterization, involving 1357 participants across multiple centers.
  • The overall incidence of RAO was found to be 9.5%, with higher occurrences in the angiography-only group compared to the PCI group (10.6% vs. 6.2%).
  • Several independent risk factors for RAO were identified, including female gender, access site cross-over, radial artery spasms, and post-catheterization use of dabigatran, while factors like performing PCI and higher doses of intravenous heparin were associated with lower odds of RAO.
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A 58-year-old male with a medical history of arterial hypertension, dyslipidemia, and psoriasis was admitted for a scheduled surgical removal of the thyroid gland. During the surgery, the patient suffered severe blood loss caused by vascular complications. After the operation, his electrocardiogram showed diffuse ST segment elevation along with high-sensitivity cardiac troponin T elevation and severe left ventricular systolic dysfunction.

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Article Synopsis
  • A 73-year-old man with a history of a drug-eluting stent in his left main stem artery experienced worsening chest pain (angina).
  • He underwent a coronary angiogram to investigate his symptoms further.
  • A myocardial perfusion SPECT scan indicated ischemia in the left anterior descending artery area.
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An emergency transradial coronary angiography in a 68-year-old woman demonstrated sub-total occlusion of the proximal left anterior descending artery.

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