Evaluation of the prognostic value of the ESTRO/EORTC classification of reirradiation in patients with non-small cell lung cancer.

Background: Retreatment with thoracic radiotherapy for recurrent, metastatic, or new primary non-small cell lung cancer (NSCLC) is increasingly used, yet evidence remains limited. This study evaluated the efficacy and safety of radical thoracic retreatment classified by the ESTRO/EORTC reirradiation definition.

Methods: This retrospective single-center study included patients with NSCLC undergoing retreatment with a second course of radical thoracic radiotherapy (≥40 Gy EQD2) between 2015 and 2023.

Safety in MR-enhanced daily adaptive SBRT Radiotherapy using a conventional C-arm linear accelerator: An FMEA approach.

Background And Purpose: MR-guided adaptive Radiotherapy has the potential to compensate for interfractional changes in patient anatomy. Modern hybrid devices, which combine MR and linear accelerator technologies, have been clinically implemented but their costs may prevent broad adoption. To accelerate the adoption of MR-guided adaptive radiotherapy, we developed a workflow for MR-enhanced daily adaptive Radiotherapy on a C-arm linac using a dedicated MR simulator and a patient transfer shuttle system.