Rapid diagnosis of alprazolam poisoning by Fourier transform infrared spectroscopy on saliva samples.

Alprazolam benzodiazepine misuse is increasingly a public health concern, evidenced by rising cases of overdose and toxicity. Timely and accurate diagnosis is crucial for effective emergency room treatment. This study investigates the use of Fourier Transform Infrared (FTIR) spectroscopy as a rapid diagnostic tool for assessing alprazolam toxicity using saliva samples.

Saliva Lipids May Determine Alprazolam Toxicity: An FTIR Study.

Background: Alprazolam, a commonly prescribed benzodiazepine, poses risks of toxicity and severe withdrawal symptoms. There is an urgent need for a rapid and sensitive diagnostic method for detecting alprazolam poisoning.

Objectives: This study aimed to detect alprazolam poisoning through Fourier-transform infrared (FTIR) analysis of saliva, addressing the need for a quick, cost-effective, and sensitive diagnostic method for poison control and differential diagnosis.