Diabetes and the risk of lung cancer.

Objective: The incidence of some cancers has been reported to be higher in diabetic patients than in the general population. We estimated the incidence of lung cancer in diabetic patients and investigated the hypothesis that the rate of lung cancer is different in diabetic compared with nondiabetic patients.

Research Design And Methods: Diabetic patients and age-, sex-, and general practice-matched nondiabetic control subjects were identified from U.

Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice.

Background: Triptans are widely used to treat migraine but have been associated with stroke, myocardial infarction (MI), and ischemic heart disease (IHD) in case reports.

Objective: To estimate the incidence of stroke, cardiovascular events, and death in a migraine cohort, stratified by triptan prescription, and investigate whether the risk of these events was increased in those treated with triptans.

Methods: Migraine patients and matched nonmigraine control subjects were identified from the General Practice Research Database.

Myocardial infarction and third generation oral contraceptives: aggregation of recent studies.

Background: Arterial cardiovascular and cerebrovascular adverse events associated with oral contraceptives (OC) are a major concern to the clinician. This paper aggregates the findings of seven recent oral contraceptive studies on the risk of acute myocardial infarction (MI) among users of second (2gen) and third (3gen) generation OC.

Methods: Odds ratios (OR) from seven original studies published between 1996 and 2001 underwent meta-analysis.