Positive Pre-Transplant Respiratory Viral PCR is Associated With Increased Day 100 Transplant-Related Mortality in Pediatric HSCT Recipients.

Background: Hematopoietic stem cell transplant (HSCT) is a curative procedure for conditions requiring the replacement of bone marrow. Respiratory viral infections (RVI) in the lower respiratory tract (LRT) cause substantial morbidity and transplant-related mortality (TRM) in pediatric transplant recipients, but the impact of mild/asymptomatic RVI is unclear. Some studies have identified certain viral infections as high risk for posttransplant complications.