Cutaneous erosions: a herald for impending pancytopenia in methotrexate toxicity.

Psoriatic plaque erosion is a rare toxic side effect of low-dose methotrexate (LDMTX) that has been reported during the treatment of psoriasis and described as a herald for impending pancytopenia. Fatalities from this have rarely been reported. Even rarer is methotrexate (MTX)-induced erosions of clinically normal skin in patients without a history of psoriasis.

Brown recluse spider bite to the upper lip.

Brown recluse spiders are predominantly found in south central United States. Their bites usually cause mild self-limiting reactions, although localized tissue necrosis and rare systemic, potentially fatal, envenomations are known to occur. Herein, we report an atypical presentation of a brown recluse bite in a 20 year old female who was admitted to the intensive care unit due to angioedema and cellulitis.

Cutaneous metastasis of breast carcinoma presenting as alopecia neoplastica.

Alopecia neoplastica is defined as hair loss secondary to a visceral malignancy that has metastasized to the scalp. We describe a woman with adenocarcinoma of the breast who developed alopecia neoplastica while receiving antineoplastic therapy. Alopecia neoplastica has been observed in 25 women.